Bile Acid Conjugates with Anticancer Activity: Most Recent Research
The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological prop...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/26/1/25 |
| _version_ | 1797543765610594304 |
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| author | Maria Luisa Navacchia Elena Marchesi Daniela Perrone |
| author_facet | Maria Luisa Navacchia Elena Marchesi Daniela Perrone |
| author_sort | Maria Luisa Navacchia |
| collection | DOAJ |
| description | The advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules. |
| first_indexed | 2024-03-10T13:50:20Z |
| format | Article |
| id | doaj.art-609696e7451e4dcf97d7751d8fa35b25 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-10T13:50:20Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-609696e7451e4dcf97d7751d8fa35b252023-11-21T02:10:18ZengMDPI AGMolecules1420-30492020-12-012612510.3390/molecules26010025Bile Acid Conjugates with Anticancer Activity: Most Recent ResearchMaria Luisa Navacchia0Elena Marchesi1Daniela Perrone2Institute of Organic Synthesis and Photoreactivity, National Research Council, Piero Gobetti 101, 40129 Bologna, ItalyDepartment of Chemical and Pharmaceutical Sciences, University of Ferrara, Luigi Borsari 46, 44121 Ferrara, ItalyDepartment of Chemical and Pharmaceutical Sciences, University of Ferrara, Luigi Borsari 46, 44121 Ferrara, ItalyThe advantages of a treatment modality that combines two or more therapeutic agents in cancer therapy encourages the study of hybrid functional compounds for pharmacological applications. In light of this, we reviewed recent works on hybrid molecules based on bile acids. Due to their biological properties, as well as their different chemical/biochemical reactive moieties, bile acids can be considered very interesting starting molecules for conjugation with natural or synthetic bioactive molecules.https://www.mdpi.com/1420-3049/26/1/25bile acids conjugatesnatural product hybridsanticancer agentspharmacological activitybioconjugationdrug design |
| spellingShingle | Maria Luisa Navacchia Elena Marchesi Daniela Perrone Bile Acid Conjugates with Anticancer Activity: Most Recent Research Molecules bile acids conjugates natural product hybrids anticancer agents pharmacological activity bioconjugation drug design |
| title | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
| title_full | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
| title_fullStr | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
| title_full_unstemmed | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
| title_short | Bile Acid Conjugates with Anticancer Activity: Most Recent Research |
| title_sort | bile acid conjugates with anticancer activity most recent research |
| topic | bile acids conjugates natural product hybrids anticancer agents pharmacological activity bioconjugation drug design |
| url | https://www.mdpi.com/1420-3049/26/1/25 |
| work_keys_str_mv | AT marialuisanavacchia bileacidconjugateswithanticanceractivitymostrecentresearch AT elenamarchesi bileacidconjugateswithanticanceractivitymostrecentresearch AT danielaperrone bileacidconjugateswithanticanceractivitymostrecentresearch |