“Just right” combinations of adjuvants with nanoscale carriers activate aged dendritic cells without overt inflammation

Abstract Background The loss in age-related immunological markers, known as immunosenescence, is caused by a combination of factors, one of which is inflammaging. Inflammaging is associated with the continuous basal generation of proinflammatory cytokines. Studies have demonstrated that inflammaging...

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Bibliographic Details
Main Authors: Ananya Ananya, Kaitlyn G. Holden, Zhiling Gu, Dan Nettleton, Surya K. Mallapragada, Michael J. Wannemuehler, Marian L. Kohut, Balaji Narasimhan
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-023-00332-0

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