Cross-sectional associations between cognition and mobility in Parkinson’s disease
ABSTRACT. Cross-sectional studies show an association of decline in mental flexibility and inhibitory control with reduced gait speed and falls, as well as divided attention deficit and difficulty in initiating gait. Objective: To investigate the relationships between cognitive function and gait pe...
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| Format: | Article |
| Language: | English |
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Associação Neurologia Cognitiva e do Comportamento
2021-04-01
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| Series: | Dementia & Neuropsychologia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000100105&tlng=en |
| _version_ | 1798014972536553472 |
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| author | Nariana Mattos Figueiredo Sousa Roberta Correa Macedo Sonia Maria Dozzi Brucki |
| author_facet | Nariana Mattos Figueiredo Sousa Roberta Correa Macedo Sonia Maria Dozzi Brucki |
| author_sort | Nariana Mattos Figueiredo Sousa |
| collection | DOAJ |
| description | ABSTRACT. Cross-sectional studies show an association of decline in mental flexibility and inhibitory control with reduced gait speed and falls, as well as divided attention deficit and difficulty in initiating gait. Objective: To investigate the relationships between cognitive function and gait performance in patients with Parkinson’s disease (PD) who participated in a hospital neurorehabilitation program. Methods: A total of 107 patients (79 males, 28 females; mean age 61.00±8.2 years; mean schooling 11.7±4.1 years) with idiopathic PD (mean disease duration 5.5±4.1 years) were recruited for this study. Among them, 78.50% were in stages I and II of the Hoehn & Yahr Scale. Cognitive functions were evaluated through the Digit Span test, Trail Making Test, and Addenbrooke’s Cognitive Examination III. Motor function was assessed with the 10-Meter Walk Test, the short version of the Balance Evaluation Systems Test (Mini-BESTest), and the Timed Up and Go Test. Results: Balance skills were significantly correlated with global cognition and specific domains, including divided attention, verbal fluency, and visuospatial function. Functional mobility showed a significant association with all cognitive tests, except for the number of errors on TMT-A. Gait speed presented a significant correlation with global cognition scores, memory, and attention, including divided attention. Conclusions: These findings might help early identification of cognitive deficits or motor dysfunctions in PD patients who may benefit from rehabilitation strategies, as well as facilitate fall risk assessments and strategies to prevent falls. Future prospective studies are needed to investigate the effects of cognitive training on motor performance, since the difficulty in motor rehabilitation may be more related to cognitive loss than to motor damage. |
| first_indexed | 2024-04-11T15:26:45Z |
| format | Article |
| id | doaj.art-609f2950fbf748129e5b2da0f8347922 |
| institution | Directory Open Access Journal |
| issn | 1980-5764 |
| language | English |
| last_indexed | 2024-04-11T15:26:45Z |
| publishDate | 2021-04-01 |
| publisher | Associação Neurologia Cognitiva e do Comportamento |
| record_format | Article |
| series | Dementia & Neuropsychologia |
| spelling | doaj.art-609f2950fbf748129e5b2da0f83479222022-12-22T04:16:14ZengAssociação Neurologia Cognitiva e do ComportamentoDementia & Neuropsychologia1980-57642021-04-0115110511110.1590/1980-57642021dn15-010011Cross-sectional associations between cognition and mobility in Parkinson’s diseaseNariana Mattos Figueiredo Sousahttps://orcid.org/0000-0001-7808-8020Roberta Correa Macedohttps://orcid.org/0000-0002-6446-7473Sonia Maria Dozzi Bruckihttps://orcid.org/0000-0002-8303-6732ABSTRACT. Cross-sectional studies show an association of decline in mental flexibility and inhibitory control with reduced gait speed and falls, as well as divided attention deficit and difficulty in initiating gait. Objective: To investigate the relationships between cognitive function and gait performance in patients with Parkinson’s disease (PD) who participated in a hospital neurorehabilitation program. Methods: A total of 107 patients (79 males, 28 females; mean age 61.00±8.2 years; mean schooling 11.7±4.1 years) with idiopathic PD (mean disease duration 5.5±4.1 years) were recruited for this study. Among them, 78.50% were in stages I and II of the Hoehn & Yahr Scale. Cognitive functions were evaluated through the Digit Span test, Trail Making Test, and Addenbrooke’s Cognitive Examination III. Motor function was assessed with the 10-Meter Walk Test, the short version of the Balance Evaluation Systems Test (Mini-BESTest), and the Timed Up and Go Test. Results: Balance skills were significantly correlated with global cognition and specific domains, including divided attention, verbal fluency, and visuospatial function. Functional mobility showed a significant association with all cognitive tests, except for the number of errors on TMT-A. Gait speed presented a significant correlation with global cognition scores, memory, and attention, including divided attention. Conclusions: These findings might help early identification of cognitive deficits or motor dysfunctions in PD patients who may benefit from rehabilitation strategies, as well as facilitate fall risk assessments and strategies to prevent falls. Future prospective studies are needed to investigate the effects of cognitive training on motor performance, since the difficulty in motor rehabilitation may be more related to cognitive loss than to motor damage.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000100105&tlng=enParkinson’s diseasegaitcognitive impairmentbalanceexecutive functions |
| spellingShingle | Nariana Mattos Figueiredo Sousa Roberta Correa Macedo Sonia Maria Dozzi Brucki Cross-sectional associations between cognition and mobility in Parkinson’s disease Dementia & Neuropsychologia Parkinson’s disease gait cognitive impairment balance executive functions |
| title | Cross-sectional associations between cognition and mobility in Parkinson’s disease |
| title_full | Cross-sectional associations between cognition and mobility in Parkinson’s disease |
| title_fullStr | Cross-sectional associations between cognition and mobility in Parkinson’s disease |
| title_full_unstemmed | Cross-sectional associations between cognition and mobility in Parkinson’s disease |
| title_short | Cross-sectional associations between cognition and mobility in Parkinson’s disease |
| title_sort | cross sectional associations between cognition and mobility in parkinson s disease |
| topic | Parkinson’s disease gait cognitive impairment balance executive functions |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1980-57642021000100105&tlng=en |
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