Thiosulfate sulfurtransferase deficiency promotes oxidative distress and aberrant NRF2 function in the brain
Thiosulfate sulfurtransferase (TST, EC 2.8.1.1) was discovered as an enzyme that detoxifies cyanide by conversion to thiocyanate (rhodanide) using thiosulfate as substrate; this rhodanese activity was subsequently identified to be almost exclusively located in mitochondria. More recently, the emphas...
Main Authors: | Yang Luo, Laurent Chatre, Shaden Melhem, Zayana M. Al-Dahmani, Natalie Z.M. Homer, Anneke Miedema, Leo E. Deelman, Matthew R. Groves, Martin Feelisch, Nicholas M. Morton, Amalia Dolga, Harry van Goor |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | Redox Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S221323172300366X |
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