Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study

BackgroundDepression during pregnancy is increasingly recognized as a worldwide public health problem. If untreated, there can be detrimental outcomes for the mother and child. Anxiety is also often comorbid with depression. Although effective treatments exist, most women do...

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Main Authors: Rachel C Vanderkruik, Craig Ferguson, Lauren A Kobylski, Joseph J Locascio, Gabriella E Hamlett, Parker C Killenberg, Robert Lewis, Noah Jones, Ella T Rossa, Hannah Dineen, Rosalind Picard, Lee S Cohen
Format: Article
Language:English
Published: JMIR Publications 2024-01-01
Series:JMIR Formative Research
Online Access:https://formative.jmir.org/2024/1/e44029
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author Rachel C Vanderkruik
Craig Ferguson
Lauren A Kobylski
Joseph J Locascio
Gabriella E Hamlett
Parker C Killenberg
Robert Lewis
Noah Jones
Ella T Rossa
Hannah Dineen
Rosalind Picard
Lee S Cohen
author_facet Rachel C Vanderkruik
Craig Ferguson
Lauren A Kobylski
Joseph J Locascio
Gabriella E Hamlett
Parker C Killenberg
Robert Lewis
Noah Jones
Ella T Rossa
Hannah Dineen
Rosalind Picard
Lee S Cohen
author_sort Rachel C Vanderkruik
collection DOAJ
description BackgroundDepression during pregnancy is increasingly recognized as a worldwide public health problem. If untreated, there can be detrimental outcomes for the mother and child. Anxiety is also often comorbid with depression. Although effective treatments exist, most women do not receive treatment. Technology is a mechanism to increase access to and engagement in mental health services. ObjectiveThe Guardians is a mobile app, grounded in behavioral activation principles, which seeks to leverage mobile game mechanics and in-game rewards to encourage user engagement. This study seeks to assess app satisfaction and engagement and to explore changes in clinical symptoms of depression and anxiety among a sample of pregnant women with elevated depressive symptoms. MethodsThis multimethod pilot test consisted of a single-arm, proof-of-concept trial to examine the feasibility and acceptability of The Guardians among a pregnant sample with depression (N=18). Participation included two web-based study visits: (1) a baseline assessment to collect demographic and obstetric information and to assess clinical symptoms and (2) an exit interview to administer follow-up measures and explore user experience. Participants completed biweekly questionnaires (ie, Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7) during the trial to assess depression and anxiety symptom severity. App satisfaction was measured using 2 self-report scales (ie, Mobile Application Rating Scale and Player Experience of Needs Satisfaction scale). Engagement with The Guardians was captured using game interaction metric data. We used backward-eliminated mixed effects longitudinal models to examine the effects of app engagement and satisfaction and length of time in the study on symptoms of depression and anxiety. Content analysis was conducted on qualitative data from exit interviews. ResultsThe 15-day and 30-day overall app retention rates were 26.6% and 15.1%, respectively. Mixed effects models found significant negative main effects of week in study (β=−.35; t61=−3.05; P=.003), number of activities completed (β=−.12; t61=−2.05; P=.04), days played (β=−.12; t58=−2.9; P=.005), and satisfaction, according to the Mobile Application Rating Scale (β=−3.05; t45=−2.19; P=.03) on depressive symptoms. We have reported about similar analyses for anxiety. There is preliminary evidence suggesting harder activities are associated with greater mood improvement than easier activities. Qualitative content analysis resulted in feedback falling under the following themes: activities, app design, engagement, fit of the app with lifestyle, perceived impact of the app on mood, and suggestions for app modifications. ConclusionsPreliminary results from this multimethod study of The Guardians indicate feasibility and acceptability among pregnant women with depression. Retention and engagement levels were more than double those of previous public mental health apps, and use of the app was associated with significant decrease in depressive symptom scores over the 10-week trial. The Guardians shows promise as an effective and scalable digital intervention to support women experiencing depression.
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spelling doaj.art-60a94bb983aa47299d209d3b852808252024-01-26T13:45:35ZengJMIR PublicationsJMIR Formative Research2561-326X2024-01-018e4402910.2196/44029Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot StudyRachel C Vanderkruikhttps://orcid.org/0000-0002-6997-7894Craig Fergusonhttps://orcid.org/0000-0003-0053-024XLauren A Kobylskihttps://orcid.org/0000-0002-0035-0516Joseph J Locasciohttps://orcid.org/0000-0003-3439-1209Gabriella E Hamletthttps://orcid.org/0000-0003-3764-2966Parker C Killenberghttps://orcid.org/0009-0009-9747-1485Robert Lewishttps://orcid.org/0000-0002-3843-7537Noah Joneshttps://orcid.org/0000-0003-4915-4142Ella T Rossahttps://orcid.org/0000-0002-2865-559XHannah Dineenhttps://orcid.org/0009-0009-0632-6363Rosalind Picardhttps://orcid.org/0000-0002-5661-0022Lee S Cohenhttps://orcid.org/0000-0003-0489-1093 BackgroundDepression during pregnancy is increasingly recognized as a worldwide public health problem. If untreated, there can be detrimental outcomes for the mother and child. Anxiety is also often comorbid with depression. Although effective treatments exist, most women do not receive treatment. Technology is a mechanism to increase access to and engagement in mental health services. ObjectiveThe Guardians is a mobile app, grounded in behavioral activation principles, which seeks to leverage mobile game mechanics and in-game rewards to encourage user engagement. This study seeks to assess app satisfaction and engagement and to explore changes in clinical symptoms of depression and anxiety among a sample of pregnant women with elevated depressive symptoms. MethodsThis multimethod pilot test consisted of a single-arm, proof-of-concept trial to examine the feasibility and acceptability of The Guardians among a pregnant sample with depression (N=18). Participation included two web-based study visits: (1) a baseline assessment to collect demographic and obstetric information and to assess clinical symptoms and (2) an exit interview to administer follow-up measures and explore user experience. Participants completed biweekly questionnaires (ie, Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7) during the trial to assess depression and anxiety symptom severity. App satisfaction was measured using 2 self-report scales (ie, Mobile Application Rating Scale and Player Experience of Needs Satisfaction scale). Engagement with The Guardians was captured using game interaction metric data. We used backward-eliminated mixed effects longitudinal models to examine the effects of app engagement and satisfaction and length of time in the study on symptoms of depression and anxiety. Content analysis was conducted on qualitative data from exit interviews. ResultsThe 15-day and 30-day overall app retention rates were 26.6% and 15.1%, respectively. Mixed effects models found significant negative main effects of week in study (β=−.35; t61=−3.05; P=.003), number of activities completed (β=−.12; t61=−2.05; P=.04), days played (β=−.12; t58=−2.9; P=.005), and satisfaction, according to the Mobile Application Rating Scale (β=−3.05; t45=−2.19; P=.03) on depressive symptoms. We have reported about similar analyses for anxiety. There is preliminary evidence suggesting harder activities are associated with greater mood improvement than easier activities. Qualitative content analysis resulted in feedback falling under the following themes: activities, app design, engagement, fit of the app with lifestyle, perceived impact of the app on mood, and suggestions for app modifications. ConclusionsPreliminary results from this multimethod study of The Guardians indicate feasibility and acceptability among pregnant women with depression. Retention and engagement levels were more than double those of previous public mental health apps, and use of the app was associated with significant decrease in depressive symptom scores over the 10-week trial. The Guardians shows promise as an effective and scalable digital intervention to support women experiencing depression.https://formative.jmir.org/2024/1/e44029
spellingShingle Rachel C Vanderkruik
Craig Ferguson
Lauren A Kobylski
Joseph J Locascio
Gabriella E Hamlett
Parker C Killenberg
Robert Lewis
Noah Jones
Ella T Rossa
Hannah Dineen
Rosalind Picard
Lee S Cohen
Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
JMIR Formative Research
title Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
title_full Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
title_fullStr Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
title_full_unstemmed Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
title_short Testing a Behavioral Activation Gaming App for Depression During Pregnancy: Multimethod Pilot Study
title_sort testing a behavioral activation gaming app for depression during pregnancy multimethod pilot study
url https://formative.jmir.org/2024/1/e44029
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