The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite
Background: A good biocomposite is a structure that can provide opportunities for cells to adhere, proliferate, and differentiate. It is affected by the characteristics of a material. As bone tissue regeneration occurs, biomaterials must have a high swelling ability and low biodegradability. The hig...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Universitas Airlangga
2023-09-01
|
| Series: | Dental Journal |
| Subjects: | |
| Online Access: | https://e-journal.unair.ac.id/MKG/article/view/39647 |
| _version_ | 1797301326948859904 |
|---|---|
| author | Titien Hary Agustantina Elly Munadziroh Anita Yuliati Muhammad Riza Hafidz Bahtiar Octarina Rizki Fauziah Salma Ajeng Putri Meyranti Fathilah Abdul Razak |
| author_facet | Titien Hary Agustantina Elly Munadziroh Anita Yuliati Muhammad Riza Hafidz Bahtiar Octarina Rizki Fauziah Salma Ajeng Putri Meyranti Fathilah Abdul Razak |
| author_sort | Titien Hary Agustantina |
| collection | DOAJ |
| description | Background: A good biocomposite is a structure that can provide opportunities for cells to adhere, proliferate, and differentiate. It is affected by the characteristics of a material. As bone tissue regeneration occurs, biomaterials must have a high swelling ability and low biodegradability. The high swelling capability will have a larger surface area that can support maximal cell attachment and proliferation on the biocomposite surface, which accelerates the regeneration process of bone defects. Purpose: The study aimed to analyze the characteristics of swelling and biodegradation of bovine amniotic membrane-hydroxyapatite (BAM-HA) biocomposite with various ratios. Methods: The BAM-HA biocomposite with a ratio of 30:70, 35:65, and 40:60 (w/w) was synthesized using a freeze-dry method. The swelling test was done by measuring the initial weight and final weight after being soaked in phosphate-buffered saline for 24 hours and the biodegradation test was done by measuring the initial weight and final weight after being soaked in simulated body fluid for seven days. Results: The swelling percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 (w/w) was 303.90%, 477.94%, and 574.19%. The biodegradation percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 was 9.43%, 11.05%, and 12.02%. Conclusion: The BAM-HA biocomposite with a ratio of 40:60 (w/w) has the highest swelling percentage while the 30:70 (w/w) ratio has the lowest percentage of biodegradation. |
| first_indexed | 2024-03-07T23:19:54Z |
| format | Article |
| id | doaj.art-60ae98f7a2f14ed59996272a0feae40e |
| institution | Directory Open Access Journal |
| issn | 1978-3728 2442-9740 |
| language | English |
| last_indexed | 2024-03-07T23:19:54Z |
| publishDate | 2023-09-01 |
| publisher | Universitas Airlangga |
| record_format | Article |
| series | Dental Journal |
| spelling | doaj.art-60ae98f7a2f14ed59996272a0feae40e2024-02-21T06:32:15ZengUniversitas AirlanggaDental Journal1978-37282442-97402023-09-0156317217710.20473/j.djmkg.v56.i3.p172-17737717The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocompositeTitien Hary Agustantina0https://orcid.org/0000-0001-6044-2722Elly Munadziroh1https://orcid.org/0000-0002-1969-2380Anita Yuliati2https://orcid.org/0000-0001-7040-0243Muhammad Riza Hafidz Bahtiar3Octarina4https://orcid.org/0000-0002-8764-8365Rizki Fauziah Salma5Ajeng Putri Meyranti6Fathilah Abdul Razak7https://orcid.org/0000-0003-3755-5950Faculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaFaculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaFaculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaFaculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaDoctoral Program, Faculty of Dental Medicine, Universitas Airlangga, Surabaya, Indonesia; Department of Dental Material, Faculty of Dentistry, Universitas Trisakti, Jakarta, IndonesiaFaculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaFaculty of Dental Medicine, Universitas Airlangga, Surabaya, IndonesiaFaculty of Dentistry, University of Malaya, Kuala Lumpur, MalaysiaBackground: A good biocomposite is a structure that can provide opportunities for cells to adhere, proliferate, and differentiate. It is affected by the characteristics of a material. As bone tissue regeneration occurs, biomaterials must have a high swelling ability and low biodegradability. The high swelling capability will have a larger surface area that can support maximal cell attachment and proliferation on the biocomposite surface, which accelerates the regeneration process of bone defects. Purpose: The study aimed to analyze the characteristics of swelling and biodegradation of bovine amniotic membrane-hydroxyapatite (BAM-HA) biocomposite with various ratios. Methods: The BAM-HA biocomposite with a ratio of 30:70, 35:65, and 40:60 (w/w) was synthesized using a freeze-dry method. The swelling test was done by measuring the initial weight and final weight after being soaked in phosphate-buffered saline for 24 hours and the biodegradation test was done by measuring the initial weight and final weight after being soaked in simulated body fluid for seven days. Results: The swelling percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 (w/w) was 303.90%, 477.94%, and 574.19%. The biodegradation percentage of BAM-HA biocomposite at each ratio of 30:70, 35:65, and 40:60 was 9.43%, 11.05%, and 12.02%. Conclusion: The BAM-HA biocomposite with a ratio of 40:60 (w/w) has the highest swelling percentage while the 30:70 (w/w) ratio has the lowest percentage of biodegradation.https://e-journal.unair.ac.id/MKG/article/view/39647biocompositebiodegradationbovine amniotic membranehydroxyapatitesocket preservationswelling |
| spellingShingle | Titien Hary Agustantina Elly Munadziroh Anita Yuliati Muhammad Riza Hafidz Bahtiar Octarina Rizki Fauziah Salma Ajeng Putri Meyranti Fathilah Abdul Razak The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite Dental Journal biocomposite biodegradation bovine amniotic membrane hydroxyapatite socket preservation swelling |
| title | The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite |
| title_full | The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite |
| title_fullStr | The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite |
| title_full_unstemmed | The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite |
| title_short | The characteristics of swelling and biodegradation tests of bovine amniotic membrane-hydroxyapatite biocomposite |
| title_sort | characteristics of swelling and biodegradation tests of bovine amniotic membrane hydroxyapatite biocomposite |
| topic | biocomposite biodegradation bovine amniotic membrane hydroxyapatite socket preservation swelling |
| url | https://e-journal.unair.ac.id/MKG/article/view/39647 |
| work_keys_str_mv | AT titienharyagustantina thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT ellymunadziroh thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT anitayuliati thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT muhammadrizahafidzbahtiar thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT octarina thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT rizkifauziahsalma thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT ajengputrimeyranti thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT fathilahabdulrazak thecharacteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT titienharyagustantina characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT ellymunadziroh characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT anitayuliati characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT muhammadrizahafidzbahtiar characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT octarina characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT rizkifauziahsalma characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT ajengputrimeyranti characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite AT fathilahabdulrazak characteristicsofswellingandbiodegradationtestsofbovineamnioticmembranehydroxyapatitebiocomposite |