Tumor-Associated Macrophages as Incessant Builders and Destroyers of the Cancer Stroma

Tumor-Associated Macrophages (TAM) are key components of the reactive stroma of tumors. In most, although not all cancers, their presence is associated with poor patient prognosis. In addition to releasing cytokines and growth factors for tumor and endothelial cells, a distinguished feature of TAM i...

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Bibliographic Details
Main Authors: Alberto Mantovani, Paola Allavena, Giovanni Germano, Graziella Solinas, Manuela Liguori
Format: Article
Language:English
Published: MDPI AG 2011-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/4/3740/

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