Tumor-Associated Macrophages as Incessant Builders and Destroyers of the Cancer Stroma
Tumor-Associated Macrophages (TAM) are key components of the reactive stroma of tumors. In most, although not all cancers, their presence is associated with poor patient prognosis. In addition to releasing cytokines and growth factors for tumor and endothelial cells, a distinguished feature of TAM i...
Main Authors: | Alberto Mantovani, Paola Allavena, Giovanni Germano, Graziella Solinas, Manuela Liguori |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2011-09-01
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Series: | Cancers |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6694/3/4/3740/ |
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