Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants
Agarwood, a highly precious non-timber fragrant wood of Aquilaria spp. (Thymelaeaceae), has been widely used in traditional medicine, religious rites, and cultural activities. Due to the inflated demanding and depleted natural resources, the yields of agarwood collected from the wild are shrinking,...
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MDPI AG
2018-02-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/23/2/342 |
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| author | Shuai Wang Zhangxin Yu Canhong Wang Chongming Wu Peng Guo Jianhe Wei |
| author_facet | Shuai Wang Zhangxin Yu Canhong Wang Chongming Wu Peng Guo Jianhe Wei |
| author_sort | Shuai Wang |
| collection | DOAJ |
| description | Agarwood, a highly precious non-timber fragrant wood of Aquilaria spp. (Thymelaeaceae), has been widely used in traditional medicine, religious rites, and cultural activities. Due to the inflated demanding and depleted natural resources, the yields of agarwood collected from the wild are shrinking, and the price is constantly rising, which restricts agarwood scientific research and wide application. With the sustainable planting and management of agarwood applied, and especially the artificial-inducing methods being used in China and Southeast Asian countries, agarwood yields are increasing, and the price is becoming more reasonable. Under this condition, illuminating the scientific nature of traditional agarwood application and developing new products and drugs from agarwood have become vitally important. Recently, the phytochemical investigations have achieved fruitful results, and more than 300 compounds have been isolated, including numerous new compounds that might be the characteristic constituents with physiological action. However, no one has focused on the new compounds and presented a summary until now. Alongside phytochemical advances, bioactivity screening and pharmacological investigation have also made a certain progress. Therefore, this review discussed the new compounds isolated after 2010, and summarized the pharmacological progress on agarwood and Aquilaria plants. |
| first_indexed | 2024-12-16T15:47:40Z |
| format | Article |
| id | doaj.art-60b9334b9a9348879d066a03dae96991 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-16T15:47:40Z |
| publishDate | 2018-02-01 |
| publisher | MDPI AG |
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| series | Molecules |
| spelling | doaj.art-60b9334b9a9348879d066a03dae969912022-12-21T22:25:45ZengMDPI AGMolecules1420-30492018-02-0123234210.3390/molecules23020342molecules23020342Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria PlantsShuai Wang0Zhangxin Yu1Canhong Wang2Chongming Wu3Peng Guo4Jianhe Wei5Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaConservation and Development of Southern Medicine, Hainan Branch of the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Haikou 570311, ChinaConservation and Development of Southern Medicine, Hainan Branch of the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Haikou 570311, ChinaPharmacology and Toxicology Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaPharmacology and Toxicology Center, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaKey Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100193, ChinaAgarwood, a highly precious non-timber fragrant wood of Aquilaria spp. (Thymelaeaceae), has been widely used in traditional medicine, religious rites, and cultural activities. Due to the inflated demanding and depleted natural resources, the yields of agarwood collected from the wild are shrinking, and the price is constantly rising, which restricts agarwood scientific research and wide application. With the sustainable planting and management of agarwood applied, and especially the artificial-inducing methods being used in China and Southeast Asian countries, agarwood yields are increasing, and the price is becoming more reasonable. Under this condition, illuminating the scientific nature of traditional agarwood application and developing new products and drugs from agarwood have become vitally important. Recently, the phytochemical investigations have achieved fruitful results, and more than 300 compounds have been isolated, including numerous new compounds that might be the characteristic constituents with physiological action. However, no one has focused on the new compounds and presented a summary until now. Alongside phytochemical advances, bioactivity screening and pharmacological investigation have also made a certain progress. Therefore, this review discussed the new compounds isolated after 2010, and summarized the pharmacological progress on agarwood and Aquilaria plants.http://www.mdpi.com/1420-3049/23/2/342agarwoodAquilaria plantschemical constitutesbioactive compoundspharmacological function |
| spellingShingle | Shuai Wang Zhangxin Yu Canhong Wang Chongming Wu Peng Guo Jianhe Wei Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants Molecules agarwood Aquilaria plants chemical constitutes bioactive compounds pharmacological function |
| title | Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants |
| title_full | Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants |
| title_fullStr | Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants |
| title_full_unstemmed | Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants |
| title_short | Chemical Constituents and Pharmacological Activity of Agarwood and Aquilaria Plants |
| title_sort | chemical constituents and pharmacological activity of agarwood and aquilaria plants |
| topic | agarwood Aquilaria plants chemical constitutes bioactive compounds pharmacological function |
| url | http://www.mdpi.com/1420-3049/23/2/342 |
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