A randomized, double-blind study on the efficacy of oral domperidone versus placebo for reducing SARS-CoV-2 viral load in mild-to-moderate COVID-19 patients in primary health care

A randomized, double-blind study on the efficacy of oral domperidone versus placebo for reducing SARS-CoV-2 viral load in mild-to-moderate COVID-19 patients in primary health care

AbstractIntroduction The clinical effect of domperidone against COVID-19 has been investigated in a double-blind phase III clinical trial (EudraCT number 2021-001228-17). Domperidone has shown in vitro antiviral activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and potent...

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Main Authors: Alejandro Rabanal Basalo, Mercedes Navarro Pablos, Nuria Viejo Pinero, María Luz Vila Méndez, Verónica Molina Barcena, Aránzazu Montilla Bernabé, María del Pilar Villanueva Morán, Ana María Blanco Gallego, Carmen Guirao Sánchez, Salvador Juárez Antón, Ángela Fernández Rodríguez, María Luisa Revuelta Puigdollers, María Teresa Sarriá Sánchez, Carmen Martín Alegre, Miguel Ángel Martínez Álvarez, María Mestre de Juan, Rebeca Mielgo Salvador, María Teresa Gijón Seco, José Manuel Saníger Herrera, María Esther Rodríguez Jiménez, Begoña Navas de la Peña, Javier Santa Cruz Hernández, Ana María Abad Esteban, Rebeca Díaz Martín, Laura García Pérez, Paloma Herrero Vanrell, María Isabel Arias de Saavedra Criado, Alexandra Vaquero Vinent, Verónica López Gómez, Víctor Manuel Montegrifo Rentero, Lucía Simón Miguel, Ignacio Campo Martos, Silvia Ortiz Zamorano, María Jesús Izquierdo Zamarriego, Izíar Vázquez Carrión, Rosa María López Valero, Carmen Gil, Ana Martínez, Begoña Soler López
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Annals of Medicine
Subjects:
SARS-CoV-2 virus
COVID-19 disease
domperidone
PCR
Online Access:https://www.tandfonline.com/doi/10.1080/07853890.2023.2268535

Internet

https://www.tandfonline.com/doi/10.1080/07853890.2023.2268535

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