Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion
Jiaming Zhou,1 Liandong Li,1 Tengshuai Li,2 Yuan Xue1 1Department of Orthopedics Surgery, Tianjin Medical University General Hospital, Heping District, Tianjin 300052, People’s Republic of China; 2Department of Orthopedics Surgery, Tianjin Hospital, Hexi District, Tianjin 300211, People&am...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-10-01
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| Series: | Journal of Pain Research |
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| Online Access: | https://www.dovepress.com/preoperative-modic-changes-are-related-to-axial-symptoms-after-anterio-peer-reviewed-article-JPR |
| _version_ | 1818488229760860160 |
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| author | Zhou J Li L Li T Xue Y |
| author_facet | Zhou J Li L Li T Xue Y |
| author_sort | Zhou J |
| collection | DOAJ |
| description | Jiaming Zhou,1 Liandong Li,1 Tengshuai Li,2 Yuan Xue1 1Department of Orthopedics Surgery, Tianjin Medical University General Hospital, Heping District, Tianjin 300052, People’s Republic of China; 2Department of Orthopedics Surgery, Tianjin Hospital, Hexi District, Tianjin 300211, People’s Republic of China Background: The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF).Materials and methods: The records of 117 patients who underwent ACDF were reviewed for clinical and radiological outcomes. These outcomes were evaluated before and after surgery and at the last follow-up. Preoperative Modic changes (MCs) adjacent to the treated disc were identified. Risk factors for AS were detected through logistic regression analysis.Results: The patients were divided into two groups: one with AS (AS group, n=35) and the other without (NAS group, n=82). Visual Analog Scale values after the operation (P=0.013) and at final follow-up (P<0.001) and preoperative segmental angle (P=0.031) were significantly different between the two groups. There were no significant differences with respect to other clinical and radiographic outcomes between the two groups (P>0.05). Logistic regression analysis revealed that preoperative segmental kyphosis (OR =2.912, P=0.035) and MCs (odds ratio =3.268, P=0.015) were the risk factors for the occurrence of AS.Conclusion: AS do not correlate with recovery of neural function in patients treated by ACDF. In addition, preoperative segmental kyphosis and MCs at the fusion segment were found to affect the incidence of AS after ACDF. Keywords: anterior cervical discectomy and fusion, cervical spondylotic myelopathy, axial symptoms, segmental angle, Modic changes |
| first_indexed | 2024-12-10T16:48:19Z |
| format | Article |
| id | doaj.art-60be58c8c3e447ec9514d933b7f9021e |
| institution | Directory Open Access Journal |
| issn | 1178-7090 |
| language | English |
| last_indexed | 2024-12-10T16:48:19Z |
| publishDate | 2018-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Pain Research |
| spelling | doaj.art-60be58c8c3e447ec9514d933b7f9021e2022-12-22T01:40:59ZengDove Medical PressJournal of Pain Research1178-70902018-10-01Volume 112617262341822Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusionZhou JLi LLi TXue YJiaming Zhou,1 Liandong Li,1 Tengshuai Li,2 Yuan Xue1 1Department of Orthopedics Surgery, Tianjin Medical University General Hospital, Heping District, Tianjin 300052, People’s Republic of China; 2Department of Orthopedics Surgery, Tianjin Hospital, Hexi District, Tianjin 300211, People’s Republic of China Background: The objective of this study was to compare the clinical and radiological outcomes between patients with or without axial symptoms (AS) and investigate the risk factors associated with AS by multivariate regression analysis in anterior cervical discectomy and fusion (ACDF).Materials and methods: The records of 117 patients who underwent ACDF were reviewed for clinical and radiological outcomes. These outcomes were evaluated before and after surgery and at the last follow-up. Preoperative Modic changes (MCs) adjacent to the treated disc were identified. Risk factors for AS were detected through logistic regression analysis.Results: The patients were divided into two groups: one with AS (AS group, n=35) and the other without (NAS group, n=82). Visual Analog Scale values after the operation (P=0.013) and at final follow-up (P<0.001) and preoperative segmental angle (P=0.031) were significantly different between the two groups. There were no significant differences with respect to other clinical and radiographic outcomes between the two groups (P>0.05). Logistic regression analysis revealed that preoperative segmental kyphosis (OR =2.912, P=0.035) and MCs (odds ratio =3.268, P=0.015) were the risk factors for the occurrence of AS.Conclusion: AS do not correlate with recovery of neural function in patients treated by ACDF. In addition, preoperative segmental kyphosis and MCs at the fusion segment were found to affect the incidence of AS after ACDF. Keywords: anterior cervical discectomy and fusion, cervical spondylotic myelopathy, axial symptoms, segmental angle, Modic changes https://www.dovepress.com/preoperative-modic-changes-are-related-to-axial-symptoms-after-anterio-peer-reviewed-article-JPRanterior cervical discectomy and fusioncervical spondylotic myelopathyaxial symptomssegmental angleModic changes |
| spellingShingle | Zhou J Li L Li T Xue Y Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion Journal of Pain Research anterior cervical discectomy and fusion cervical spondylotic myelopathy axial symptoms segmental angle Modic changes |
| title | Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| title_full | Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| title_fullStr | Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| title_full_unstemmed | Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| title_short | Preoperative Modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| title_sort | preoperative modic changes are related to axial symptoms after anterior cervical discectomy and fusion |
| topic | anterior cervical discectomy and fusion cervical spondylotic myelopathy axial symptoms segmental angle Modic changes |
| url | https://www.dovepress.com/preoperative-modic-changes-are-related-to-axial-symptoms-after-anterio-peer-reviewed-article-JPR |
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