A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis

The exocytosis of synaptic vesicles (SVs) elicited by potent stimulation is rapidly compensated by bulk endocytosis of SV membranes leading to large endocytic vacuoles (‘bulk’ endosomes). Subsequently, these vacuoles disappear in parallel with the reappearance of new SVs. We have used synapses of dy...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Yumei Wu, Eileen T O'Toole, Martine Girard, Brigitte Ritter, Mirko Messa, Xinran Liu, Peter S McPherson, Shawn M Ferguson, Pietro De Camilli
Format: Artikel
Sprache:English
Veröffentlicht: eLife Sciences Publications Ltd 2014-06-01
Schriftenreihe:eLife
Schlagworte:
Online Zugang:https://elifesciences.org/articles/01621