Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection
Dopamine (DA) is an essential neurotransmitter which plays important roles in human’s biological and cognitive processes, specifically learning, memory, emotions, and movements. Abnormality of dopamine level can signal the trace of neurological diseases. Dopamine detection, therefore, can be useful...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
IOP Publishing
2019-01-01
|
| Series: | Materials Research Express |
| Subjects: | |
| Online Access: | https://doi.org/10.1088/2053-1591/ab59ff |
| _version_ | 1797747144613953536 |
|---|---|
| author | Nicha Sato Makito Haruta Yasumi Ohta Kiyotaka Sasagawa Jun Ohta Naray Pewnim Oratai Jongprateep |
| author_facet | Nicha Sato Makito Haruta Yasumi Ohta Kiyotaka Sasagawa Jun Ohta Naray Pewnim Oratai Jongprateep |
| author_sort | Nicha Sato |
| collection | DOAJ |
| description | Dopamine (DA) is an essential neurotransmitter which plays important roles in human’s biological and cognitive processes, specifically learning, memory, emotions, and movements. Abnormality of dopamine level can signal the trace of neurological diseases. Dopamine detection, therefore, can be useful in detection of symptoms and diseases related to brain disorders such as Parkinson’s and depression. This study aimed at examining usage of hematite iron oxide (Fe _2 O _3 ) as electrochemical sensors for dopamine detection. Nanoparticulate Fe _2 O _3 was synthesized, microstructurally examined, and tested for its electrocatalytic activities. The synthesized powder showed a single phase with an average particle size of 93.9 nm. Electrocatalytic activities of the powder, measured in dopamine hydrochloride solutions with concentrations ranging from 0.1 to 10 μ M, were evaluated by cyclic voltammetry technique. At applied voltage of 0.33 V, peak currents corresponding to oxidation reactions between dopamine and Fe _2 O _3 electrode were detected. With sensitivity of Fe _2 O _3 electrode in the range between 0.021 and 0.033 μ A μ M ^−1 , the Fe _2 O _3 nanoparticles exhibited fair sensing ability. |
| first_indexed | 2024-03-12T15:46:58Z |
| format | Article |
| id | doaj.art-60cc11fdd6894231b32a642acbf4f5b1 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:46:58Z |
| publishDate | 2019-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-60cc11fdd6894231b32a642acbf4f5b12023-08-09T15:23:08ZengIOP PublishingMaterials Research Express2053-15912019-01-017101570110.1088/2053-1591/ab59ffFe2O3/MWCNTs modified microdialysis electrode for dopamine detectionNicha Sato0Makito Haruta1Yasumi Ohta2Kiyotaka Sasagawa3Jun Ohta4https://orcid.org/0000-0001-8194-9020Naray Pewnim5Oratai Jongprateep6https://orcid.org/0000-0001-5160-5091Department of Materials Engineering, Faculty of Engineering, Kasetsart University , Bangkok, ThailandDivision of Materials Science, Nara Institute of Science and Technology, Nara, JapanDivision of Materials Science, Nara Institute of Science and Technology, Nara, JapanDivision of Materials Science, Nara Institute of Science and Technology, Nara, JapanDivision of Materials Science, Nara Institute of Science and Technology, Nara, JapanDepartment of Materials Engineering, Faculty of Engineering, Kasetsart University , Bangkok, ThailandDepartment of Materials Engineering, Faculty of Engineering, Kasetsart University , Bangkok, Thailand; Materials Innovation Center, Faculty of Engineering, Kasetsart University , Bangkok, ThailandDopamine (DA) is an essential neurotransmitter which plays important roles in human’s biological and cognitive processes, specifically learning, memory, emotions, and movements. Abnormality of dopamine level can signal the trace of neurological diseases. Dopamine detection, therefore, can be useful in detection of symptoms and diseases related to brain disorders such as Parkinson’s and depression. This study aimed at examining usage of hematite iron oxide (Fe _2 O _3 ) as electrochemical sensors for dopamine detection. Nanoparticulate Fe _2 O _3 was synthesized, microstructurally examined, and tested for its electrocatalytic activities. The synthesized powder showed a single phase with an average particle size of 93.9 nm. Electrocatalytic activities of the powder, measured in dopamine hydrochloride solutions with concentrations ranging from 0.1 to 10 μ M, were evaluated by cyclic voltammetry technique. At applied voltage of 0.33 V, peak currents corresponding to oxidation reactions between dopamine and Fe _2 O _3 electrode were detected. With sensitivity of Fe _2 O _3 electrode in the range between 0.021 and 0.033 μ A μ M ^−1 , the Fe _2 O _3 nanoparticles exhibited fair sensing ability.https://doi.org/10.1088/2053-1591/ab59ffiron oxidecombustion synthesisnanoparticulateelectrocatalyticdopamine |
| spellingShingle | Nicha Sato Makito Haruta Yasumi Ohta Kiyotaka Sasagawa Jun Ohta Naray Pewnim Oratai Jongprateep Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection Materials Research Express iron oxide combustion synthesis nanoparticulate electrocatalytic dopamine |
| title | Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection |
| title_full | Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection |
| title_fullStr | Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection |
| title_full_unstemmed | Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection |
| title_short | Fe2O3/MWCNTs modified microdialysis electrode for dopamine detection |
| title_sort | fe2o3 mwcnts modified microdialysis electrode for dopamine detection |
| topic | iron oxide combustion synthesis nanoparticulate electrocatalytic dopamine |
| url | https://doi.org/10.1088/2053-1591/ab59ff |
| work_keys_str_mv | AT nichasato fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT makitoharuta fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT yasumiohta fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT kiyotakasasagawa fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT junohta fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT naraypewnim fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection AT orataijongprateep fe2o3mwcntsmodifiedmicrodialysiselectrodefordopaminedetection |