Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis
Purpose: To assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation. Methods: Retrospectively, data of patient...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=1;spage=69;epage=74;aulast=Jinagal |
| _version_ | 1818878320959291392 |
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| author | Jitender Jinagal Gaurav Gupta Aniruddha Agarwal Kanika Aggarwal Madhuri Akella Vishali Gupta Deepti Suri Anju Gupta Surjit Singh Jagat Ram |
| author_facet | Jitender Jinagal Gaurav Gupta Aniruddha Agarwal Kanika Aggarwal Madhuri Akella Vishali Gupta Deepti Suri Anju Gupta Surjit Singh Jagat Ram |
| author_sort | Jitender Jinagal |
| collection | DOAJ |
| description | Purpose: To assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation. Methods: Retrospectively, data of patients with JIA-associated uveitis undergoing phacoemulsification with PCIOL implantation with intraoperative dexamethasone implant injection were analyzed. Patients with a minimum follow-up of 6 months were included. Primary outcome measures were ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis. Results: 8 eyes of 6 patients were included. BCVA was significantly improved at 1, 3, and 6 months postoperatively 0.20 ± 0.09, P = 0.008; 0.18 ± 0.11, P = 0.008; and 0.24 ± 0.11, P = 0.01, respectively. No statistical difference noted in mean IOP at various follow-up visits. None developed worsening of uveitis or Cystoid macular edema. Conclusion: Intraoperative intravitreal dexamethasone implant is a safe and effective in preventing and managing the postoperative inflammation in children with JIA-associated uveitic cataract. |
| first_indexed | 2024-12-19T14:12:19Z |
| format | Article |
| id | doaj.art-60ce72812fa44c85a0635bdb62e9021c |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-12-19T14:12:19Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-60ce72812fa44c85a0635bdb62e9021c2022-12-21T20:18:05ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892019-01-01671697410.4103/ijo.IJO_713_18Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitisJitender JinagalGaurav GuptaAniruddha AgarwalKanika AggarwalMadhuri AkellaVishali GuptaDeepti SuriAnju GuptaSurjit SinghJagat RamPurpose: To assess the safety and efficacy of intraoperative intravitreal dexamethasone implant in patients of juvenile idiopathic arthritis (JIA)-associated uveitis undergoing phacoemulsification with posterior chamber intraocular lens (PCIOL) implantation. Methods: Retrospectively, data of patients with JIA-associated uveitis undergoing phacoemulsification with PCIOL implantation with intraoperative dexamethasone implant injection were analyzed. Patients with a minimum follow-up of 6 months were included. Primary outcome measures were ocular inflammation, intraocular pressure (IOP), best-corrected visual acuity (BCVA), and worsening of uveitis. Results: 8 eyes of 6 patients were included. BCVA was significantly improved at 1, 3, and 6 months postoperatively 0.20 ± 0.09, P = 0.008; 0.18 ± 0.11, P = 0.008; and 0.24 ± 0.11, P = 0.01, respectively. No statistical difference noted in mean IOP at various follow-up visits. None developed worsening of uveitis or Cystoid macular edema. Conclusion: Intraoperative intravitreal dexamethasone implant is a safe and effective in preventing and managing the postoperative inflammation in children with JIA-associated uveitic cataract.http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=1;spage=69;epage=74;aulast=JinagalChildrencataract surgerydexamethasone implantJIAjuvenile idiopathic arthritisphacoemulsificationuveitis |
| spellingShingle | Jitender Jinagal Gaurav Gupta Aniruddha Agarwal Kanika Aggarwal Madhuri Akella Vishali Gupta Deepti Suri Anju Gupta Surjit Singh Jagat Ram Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis Indian Journal of Ophthalmology Children cataract surgery dexamethasone implant JIA juvenile idiopathic arthritis phacoemulsification uveitis |
| title | Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| title_full | Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| title_fullStr | Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| title_full_unstemmed | Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| title_short | Safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| title_sort | safety and efficacy of dexamethasone implant along with phacoemulsification and intraocular lens implantation in children with juvenile idiopathic arthritis associated uveitis |
| topic | Children cataract surgery dexamethasone implant JIA juvenile idiopathic arthritis phacoemulsification uveitis |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2019;volume=67;issue=1;spage=69;epage=74;aulast=Jinagal |
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