Clinical analysis of respiratory depression caused by glufosinate poisoning
ObjectiveTo analyze the clinical features， treatment and prognosis of patients with respiratory depression caused by glufosinate poisoning.MethodsThe clinical data of patients with respiratory depression caused by glufosinate poisoning admitted to the ICU of Xiangshan first people’s hospital medical...
| Main Authors: | , |
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| Format: | Article |
| Language: | zho |
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Shanghai Preventive Medicine Association
2023-05-01
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| Series: | Shanghai yufang yixue |
| Subjects: | |
| Online Access: | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22564 |
| _version_ | 1797772390482051072 |
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| author | SUN Chaonan CHENG Hongsen |
| author_facet | SUN Chaonan CHENG Hongsen |
| author_sort | SUN Chaonan |
| collection | DOAJ |
| description | ObjectiveTo analyze the clinical features， treatment and prognosis of patients with respiratory depression caused by glufosinate poisoning.MethodsThe clinical data of patients with respiratory depression caused by glufosinate poisoning admitted to the ICU of Xiangshan first people’s hospital medical and health group from March 2018 to January 2022 were retrospectively analyzed.ResultsA total of 21 patients with respiratory depression caused by glufosinate poisoning were included. The median （interquartile） intake of glufosinate was 30 （20， 40） g， and the median （interquartile） visit time was within 2.0 （1.0， 2.8） h. The initial symptoms were nausea and vomiting in 16 cases （76.2%）， and sore throat in 8 cases （38.1%）. Respiratory depression， convulsions and shock occurred 6‒48 hours after ingestion of glufosinate. Convulsion occurred in 13 cases （61.9%）， shock in 10 cases （47.6%） and bradycardia in 5 cases （23.8 %）. Among the patients with convulsion or shock， respiratory depression occurred earlier than convulsion and shock in 10 cases （76.9%） and 9 cases （90.0%）， respectively. All patients were treated with gastric lavage， catharsis， mechanical ventilation and symptomatic support. Blood purification was performed in 14 cases. The duration of mechanical ventilation was 5.0 （4.0， 7.0） d，and no patient died. The patients were divided into blood purification group and routine treatment group. There was no significant difference in complications and duration of mechanical ventilation between the blood purification group and the routine treatment group （P>0.05）.ConclusionRespiratory depression caused by glufosinate poisoning usually occurs earlier than convulsion and shock. The overall prognosis of patients with respiratory depression caused by glufosinate poisoning is good， which mainly depends on the early recognition and intervention of respiratory depression. |
| first_indexed | 2024-03-12T21:51:09Z |
| format | Article |
| id | doaj.art-60cf9e22a44a4872a0bdbfc5a8b549f1 |
| institution | Directory Open Access Journal |
| issn | 1004-9231 |
| language | zho |
| last_indexed | 2024-03-12T21:51:09Z |
| publishDate | 2023-05-01 |
| publisher | Shanghai Preventive Medicine Association |
| record_format | Article |
| series | Shanghai yufang yixue |
| spelling | doaj.art-60cf9e22a44a4872a0bdbfc5a8b549f12023-07-26T03:00:11ZzhoShanghai Preventive Medicine AssociationShanghai yufang yixue1004-92312023-05-0135550050410.19428/j.cnki.sjpm.2023.225641004-9231（2023）05-0500-05Clinical analysis of respiratory depression caused by glufosinate poisoningSUN ChaonanCHENG HongsenObjectiveTo analyze the clinical features， treatment and prognosis of patients with respiratory depression caused by glufosinate poisoning.MethodsThe clinical data of patients with respiratory depression caused by glufosinate poisoning admitted to the ICU of Xiangshan first people’s hospital medical and health group from March 2018 to January 2022 were retrospectively analyzed.ResultsA total of 21 patients with respiratory depression caused by glufosinate poisoning were included. The median （interquartile） intake of glufosinate was 30 （20， 40） g， and the median （interquartile） visit time was within 2.0 （1.0， 2.8） h. The initial symptoms were nausea and vomiting in 16 cases （76.2%）， and sore throat in 8 cases （38.1%）. Respiratory depression， convulsions and shock occurred 6‒48 hours after ingestion of glufosinate. Convulsion occurred in 13 cases （61.9%）， shock in 10 cases （47.6%） and bradycardia in 5 cases （23.8 %）. Among the patients with convulsion or shock， respiratory depression occurred earlier than convulsion and shock in 10 cases （76.9%） and 9 cases （90.0%）， respectively. All patients were treated with gastric lavage， catharsis， mechanical ventilation and symptomatic support. Blood purification was performed in 14 cases. The duration of mechanical ventilation was 5.0 （4.0， 7.0） d，and no patient died. The patients were divided into blood purification group and routine treatment group. There was no significant difference in complications and duration of mechanical ventilation between the blood purification group and the routine treatment group （P>0.05）.ConclusionRespiratory depression caused by glufosinate poisoning usually occurs earlier than convulsion and shock. The overall prognosis of patients with respiratory depression caused by glufosinate poisoning is good， which mainly depends on the early recognition and intervention of respiratory depression.http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22564glufosinatepoisoningrespiratory depressionblood purification |
| spellingShingle | SUN Chaonan CHENG Hongsen Clinical analysis of respiratory depression caused by glufosinate poisoning Shanghai yufang yixue glufosinate poisoning respiratory depression blood purification |
| title | Clinical analysis of respiratory depression caused by glufosinate poisoning |
| title_full | Clinical analysis of respiratory depression caused by glufosinate poisoning |
| title_fullStr | Clinical analysis of respiratory depression caused by glufosinate poisoning |
| title_full_unstemmed | Clinical analysis of respiratory depression caused by glufosinate poisoning |
| title_short | Clinical analysis of respiratory depression caused by glufosinate poisoning |
| title_sort | clinical analysis of respiratory depression caused by glufosinate poisoning |
| topic | glufosinate poisoning respiratory depression blood purification |
| url | http://www.sjpm.org.cn/article/doi/10.19428/j.cnki.sjpm.2023.22564 |
| work_keys_str_mv | AT sunchaonan clinicalanalysisofrespiratorydepressioncausedbyglufosinatepoisoning AT chenghongsen clinicalanalysisofrespiratorydepressioncausedbyglufosinatepoisoning |