Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications

Abstract Anthropogenic carbon dioxide (CO2) levels are rising to alarming concentrations in earth’s atmosphere, causing adverse effects and global climate changes. In the last century, innovative research on CO2 reduction using chemical, photochemical, electrochemical and enzymatic approaches has be...

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Main Authors: Rebecca Bährle, Stefanie Böhnke, Jonas Englhard, Julien Bachmann, Mirjam Perner
Format: Article
Language:English
Published: SpringerOpen 2023-11-01
Series:Bioresources and Bioprocessing
Subjects:
Online Access:https://doi.org/10.1186/s40643-023-00705-9
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author Rebecca Bährle
Stefanie Böhnke
Jonas Englhard
Julien Bachmann
Mirjam Perner
author_facet Rebecca Bährle
Stefanie Böhnke
Jonas Englhard
Julien Bachmann
Mirjam Perner
author_sort Rebecca Bährle
collection DOAJ
description Abstract Anthropogenic carbon dioxide (CO2) levels are rising to alarming concentrations in earth’s atmosphere, causing adverse effects and global climate changes. In the last century, innovative research on CO2 reduction using chemical, photochemical, electrochemical and enzymatic approaches has been addressed. In particular, natural CO2 conversion serves as a model for many processes and extensive studies on microbes and enzymes regarding redox reactions involving CO2 have already been conducted. In this review we focus on the enzymatic conversion of CO2 to carbon monoxide (CO) as the chemical conversion downstream of CO production render CO particularly attractive as a key intermediate. We briefly discuss the different currently known natural autotrophic CO2 fixation pathways, focusing on the reversible reaction of CO2, two electrons and protons to CO and water, catalyzed by carbon monoxide dehydrogenases (CODHs). We then move on to classify the different type of CODHs, involved catalyzed chemical reactions and coupled metabolisms. Finally, we discuss applications of CODH enzymes in photochemical and electrochemical cells to harness CO2 from the environment transforming it into commodity chemicals.
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spelling doaj.art-60d0af529ee44e80922c1b62392a98c32024-03-31T11:09:23ZengSpringerOpenBioresources and Bioprocessing2197-43652023-11-0110111910.1186/s40643-023-00705-9Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applicationsRebecca Bährle0Stefanie Böhnke1Jonas Englhard2Julien Bachmann3Mirjam Perner4Department of Marine Geomicrobiology, Faculty of Marine Biogeochemistry, GEOMAR Helmholtz Centre for Ocean Research KielDepartment of Marine Geomicrobiology, Faculty of Marine Biogeochemistry, GEOMAR Helmholtz Centre for Ocean Research KielChemistry of Thin Film Materials, IZNF, Friedrich-Alexander-Universität Erlangen-NürnbergChemistry of Thin Film Materials, IZNF, Friedrich-Alexander-Universität Erlangen-NürnbergDepartment of Marine Geomicrobiology, Faculty of Marine Biogeochemistry, GEOMAR Helmholtz Centre for Ocean Research KielAbstract Anthropogenic carbon dioxide (CO2) levels are rising to alarming concentrations in earth’s atmosphere, causing adverse effects and global climate changes. In the last century, innovative research on CO2 reduction using chemical, photochemical, electrochemical and enzymatic approaches has been addressed. In particular, natural CO2 conversion serves as a model for many processes and extensive studies on microbes and enzymes regarding redox reactions involving CO2 have already been conducted. In this review we focus on the enzymatic conversion of CO2 to carbon monoxide (CO) as the chemical conversion downstream of CO production render CO particularly attractive as a key intermediate. We briefly discuss the different currently known natural autotrophic CO2 fixation pathways, focusing on the reversible reaction of CO2, two electrons and protons to CO and water, catalyzed by carbon monoxide dehydrogenases (CODHs). We then move on to classify the different type of CODHs, involved catalyzed chemical reactions and coupled metabolisms. Finally, we discuss applications of CODH enzymes in photochemical and electrochemical cells to harness CO2 from the environment transforming it into commodity chemicals.https://doi.org/10.1186/s40643-023-00705-9CO2 fixing microorganismsCarbon monoxide dehydrogenase (CODH)CO2 reductionElectrocatalysisBiocatalysts
spellingShingle Rebecca Bährle
Stefanie Böhnke
Jonas Englhard
Julien Bachmann
Mirjam Perner
Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
Bioresources and Bioprocessing
CO2 fixing microorganisms
Carbon monoxide dehydrogenase (CODH)
CO2 reduction
Electrocatalysis
Biocatalysts
title Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
title_full Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
title_fullStr Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
title_full_unstemmed Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
title_short Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications
title_sort current status of carbon monoxide dehydrogenases codh and their potential for electrochemical applications
topic CO2 fixing microorganisms
Carbon monoxide dehydrogenase (CODH)
CO2 reduction
Electrocatalysis
Biocatalysts
url https://doi.org/10.1186/s40643-023-00705-9
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