Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial

Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial

Abstract Background A defining feature of prolonged critical illness is muscle wasting, leading to impaired recovery. Supplementation with a tailored blend of amino acids may bolster the innate gut defence, promote intestinal mucosa repair and limit muscle loss. Methods This was a monocentric, rando...

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Bibliographic Details
Main Authors: Nicholas Heming, Robert Carlier, Helene Prigent, Ahmed Mekki, Camille Jousset, Frederic Lofaso, Xavier Ambrosi, Rania Bounab, Virginie Maxime, Arnaud Mansart, Pascal Crenn, Pierre Moine, Fabien Foltzer, Bernard Cuenoud, Tobias Konz, John Corthesy, Maurice Beaumont, Mickaël Hartweg, Claudia Roessle, Jean-Charles Preiser, Denis Breuillé, Djillali Annane
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Critical Care
Subjects:
Sepsis
Critical illness
Protein balance
Intensive care unit
Nutrition
Online Access:https://doi.org/10.1186/s13054-022-04232-5

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