Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs
Objective Astragalus membranaceus root is a well-known traditional Chinese herbal medicine with many biological active constituents. This study was conducted to examine the effects of Astragalus membranaceus root powder (AMP) on growth performance, serum antioxidant and immune response in finishing...
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| Format: | Article |
| Language: | English |
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Asian-Australasian Association of Animal Production Societies
2020-06-01
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| Series: | Asian-Australasian Journal of Animal Sciences |
| Subjects: | |
| Online Access: | http://www.ajas.info/upload/pdf/ajas-19-0295.pdf |
| _version_ | 1818850434468544512 |
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| author | Xiaoyan Hao Pengju Wang Youshe Ren Gentang Liu Jianxin Zhang Brian Leury Chunxiang Zhang |
| author_facet | Xiaoyan Hao Pengju Wang Youshe Ren Gentang Liu Jianxin Zhang Brian Leury Chunxiang Zhang |
| author_sort | Xiaoyan Hao |
| collection | DOAJ |
| description | Objective Astragalus membranaceus root is a well-known traditional Chinese herbal medicine with many biological active constituents. This study was conducted to examine the effects of Astragalus membranaceus root powder (AMP) on growth performance, serum antioxidant and immune response in finishing lambs. Methods A total of thirty-six Guangling fat-tailed ram lambs (body weight = 19±2 kg, mean ±standard deviation) were randomly assigned to one of six treatments for a 40 d feeding period, with the first 10 d for adaptation. Treatments consisted of the lambs’ basal diets with addition of 0, 5, 10, 15, 20, and 30 g/kg of diet of AMP. Results Response to supplementation level of AMP was quadratic (p≤0.032) for final weight and ADG with the greatest at 10 g/kg of diet, but dry matter intake was not affected (p≥ 0.227) by treatments. The increase of AMP supplementation resulted in a quadratic response in contents of triglyceride and creatinine (p<0.05), with the lowest values for 10 and 20 g/kg of diet, respectively. A linear and quadratic decrease was observed in activity of alkaline phosphatase in serum of lambs. As the AMP supplementation increased, the activities of total superoxide dismutase and total antioxidant capacity increased linearly (p≤0.018) and hydroxyl radical (OH−) decreased linearly (p = 0.002). For catalase (CAT) and malondialdehyde (MDA), quadratic (p≤0.001) effects were observed among treatments, with the greatest CAT and lowest MDA values at 10 g/kg AMP. Additionally, supplementing AMP up to a level of 10 or 15 g/kg of diet quadratically increased immunoglobulin and interleukin contents in the serum. Conclusion The results indicated that AMP can be used as natural feed additive in the ration of lambs to improve ADG, antioxidant status, and immune functions, and the optimal dose was 10 g/kg of diet under the condition of this experiment. |
| first_indexed | 2024-12-19T06:49:04Z |
| format | Article |
| id | doaj.art-60d8255017ed4c9da74c9196831df111 |
| institution | Directory Open Access Journal |
| issn | 1011-2367 1976-5517 |
| language | English |
| last_indexed | 2024-12-19T06:49:04Z |
| publishDate | 2020-06-01 |
| publisher | Asian-Australasian Association of Animal Production Societies |
| record_format | Article |
| series | Asian-Australasian Journal of Animal Sciences |
| spelling | doaj.art-60d8255017ed4c9da74c9196831df1112022-12-21T20:31:50ZengAsian-Australasian Association of Animal Production SocietiesAsian-Australasian Journal of Animal Sciences1011-23671976-55172020-06-0133696597210.5713/ajas.19.029524354Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambsXiaoyan Hao0Pengju Wang1Youshe Ren2Gentang Liu3Jianxin Zhang4Brian Leury5Chunxiang Zhang6 College of Animal Science and Veterinary, Shanxi Agricultural University, Taigu 030801, China College of Animal Science and Veterinary, Shanxi Agricultural University, Taigu 030801, China College of Animal Science and Veterinary, Shanxi Agricultural University, Taigu 030801, China Institution of Husbandry and Veterinary, Yingxian 037600, China College of Animal Science and Veterinary, Shanxi Agricultural University, Taigu 030801, China Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Victoria 3010, Australia College of Animal Science and Veterinary, Shanxi Agricultural University, Taigu 030801, ChinaObjective Astragalus membranaceus root is a well-known traditional Chinese herbal medicine with many biological active constituents. This study was conducted to examine the effects of Astragalus membranaceus root powder (AMP) on growth performance, serum antioxidant and immune response in finishing lambs. Methods A total of thirty-six Guangling fat-tailed ram lambs (body weight = 19±2 kg, mean ±standard deviation) were randomly assigned to one of six treatments for a 40 d feeding period, with the first 10 d for adaptation. Treatments consisted of the lambs’ basal diets with addition of 0, 5, 10, 15, 20, and 30 g/kg of diet of AMP. Results Response to supplementation level of AMP was quadratic (p≤0.032) for final weight and ADG with the greatest at 10 g/kg of diet, but dry matter intake was not affected (p≥ 0.227) by treatments. The increase of AMP supplementation resulted in a quadratic response in contents of triglyceride and creatinine (p<0.05), with the lowest values for 10 and 20 g/kg of diet, respectively. A linear and quadratic decrease was observed in activity of alkaline phosphatase in serum of lambs. As the AMP supplementation increased, the activities of total superoxide dismutase and total antioxidant capacity increased linearly (p≤0.018) and hydroxyl radical (OH−) decreased linearly (p = 0.002). For catalase (CAT) and malondialdehyde (MDA), quadratic (p≤0.001) effects were observed among treatments, with the greatest CAT and lowest MDA values at 10 g/kg AMP. Additionally, supplementing AMP up to a level of 10 or 15 g/kg of diet quadratically increased immunoglobulin and interleukin contents in the serum. Conclusion The results indicated that AMP can be used as natural feed additive in the ration of lambs to improve ADG, antioxidant status, and immune functions, and the optimal dose was 10 g/kg of diet under the condition of this experiment.http://www.ajas.info/upload/pdf/ajas-19-0295.pdf rootgrowth performanceantioxidant statusimmune responselamb |
| spellingShingle | Xiaoyan Hao Pengju Wang Youshe Ren Gentang Liu Jianxin Zhang Brian Leury Chunxiang Zhang Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs Asian-Australasian Journal of Animal Sciences root growth performance antioxidant status immune response lamb |
| title | Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs |
| title_full | Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs |
| title_fullStr | Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs |
| title_full_unstemmed | Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs |
| title_short | Effects of roots supplementation on growth performance, serum antioxidant and immune response in finishing lambs |
| title_sort | effects of roots supplementation on growth performance serum antioxidant and immune response in finishing lambs |
| topic | root growth performance antioxidant status immune response lamb |
| url | http://www.ajas.info/upload/pdf/ajas-19-0295.pdf |
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