Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort
BackgroundEpidemiological studies provide limited information on the relationship between dairy consumption and the incidence of esophagus cancer (EC). We examined whether eating dairy foods is associated with a lower risk of EC in an American population.MethodsIn our study, we analyzed data from th...
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| Format: | Article |
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Frontiers Media S.A.
2022-12-01
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| Series: | Frontiers in Nutrition |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnut.2022.1015062/full |
| _version_ | 1828091303114571776 |
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| author | Tingting Wang Yi Zhu Yuanzhu Zheng Yang Cao Qin Xu Xiangan Wang Wenli Hu Yun Zhang Yun Zhang |
| author_facet | Tingting Wang Yi Zhu Yuanzhu Zheng Yang Cao Qin Xu Xiangan Wang Wenli Hu Yun Zhang Yun Zhang |
| author_sort | Tingting Wang |
| collection | DOAJ |
| description | BackgroundEpidemiological studies provide limited information on the relationship between dairy consumption and the incidence of esophagus cancer (EC). We examined whether eating dairy foods is associated with a lower risk of EC in an American population.MethodsIn our study, we analyzed data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial, which included 101,723 subjects. Dairy product consumption was assessed using a dietary history questionnaire. We used Cox regression and restricted cubic splines to assess whether dairy consumption is associated with EC incidence.ResultsA total of 154 EC cases were identified after a median follow-up of 12.2 years. After adjusting for confounders, we discovered no statistically significant correlation between total dairy product consumption and EC risk (HR with 95% CI for ≥1.79 servings/day vs. ≤0.6 servings/day: 0.83, 0.50–1.38; p for trend = 0.465). Additionally, no associations were found between EC risk and other dairy foods such as milk, yogurt, and cheese.ConclusionWe concluded that the findings of the PLCO cohort do not suggest dairy consumption reduces the risk of EC. |
| first_indexed | 2024-04-11T06:10:50Z |
| format | Article |
| id | doaj.art-60d94faa199b49faab829f64f6766fbc |
| institution | Directory Open Access Journal |
| issn | 2296-861X |
| language | English |
| last_indexed | 2024-04-11T06:10:50Z |
| publishDate | 2022-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Nutrition |
| spelling | doaj.art-60d94faa199b49faab829f64f6766fbc2022-12-22T04:41:17ZengFrontiers Media S.A.Frontiers in Nutrition2296-861X2022-12-01910.3389/fnut.2022.10150621015062Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohortTingting Wang0Yi Zhu1Yuanzhu Zheng2Yang Cao3Qin Xu4Xiangan Wang5Wenli Hu6Yun Zhang7Yun Zhang8Department of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Communicable Diseases Control and Prevention, Hangzhou Center for Disease Control and Prevention, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Nutrition, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaDepartment of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, ChinaBackgroundEpidemiological studies provide limited information on the relationship between dairy consumption and the incidence of esophagus cancer (EC). We examined whether eating dairy foods is associated with a lower risk of EC in an American population.MethodsIn our study, we analyzed data from the Prostate, Lung, Colorectal, and Ovarian (PLCO) cancer screening trial, which included 101,723 subjects. Dairy product consumption was assessed using a dietary history questionnaire. We used Cox regression and restricted cubic splines to assess whether dairy consumption is associated with EC incidence.ResultsA total of 154 EC cases were identified after a median follow-up of 12.2 years. After adjusting for confounders, we discovered no statistically significant correlation between total dairy product consumption and EC risk (HR with 95% CI for ≥1.79 servings/day vs. ≤0.6 servings/day: 0.83, 0.50–1.38; p for trend = 0.465). Additionally, no associations were found between EC risk and other dairy foods such as milk, yogurt, and cheese.ConclusionWe concluded that the findings of the PLCO cohort do not suggest dairy consumption reduces the risk of EC.https://www.frontiersin.org/articles/10.3389/fnut.2022.1015062/fulldairy productesophagus cancerPLCOcohortrisk |
| spellingShingle | Tingting Wang Yi Zhu Yuanzhu Zheng Yang Cao Qin Xu Xiangan Wang Wenli Hu Yun Zhang Yun Zhang Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort Frontiers in Nutrition dairy product esophagus cancer PLCO cohort risk |
| title | Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort |
| title_full | Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort |
| title_fullStr | Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort |
| title_full_unstemmed | Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort |
| title_short | Dairy consumption and risk of esophagus cancer in the prostate, lung, colorectal, and ovarian cohort |
| title_sort | dairy consumption and risk of esophagus cancer in the prostate lung colorectal and ovarian cohort |
| topic | dairy product esophagus cancer PLCO cohort risk |
| url | https://www.frontiersin.org/articles/10.3389/fnut.2022.1015062/full |
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