Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018
Abstract Background The multimorbidity of Atherosclerotic cardiovascular disease (ASCVD) and many other chronic conditions is becoming common. This study aimed to assess multimorbidity distribution in ASCVD among adults in the United States from 1999 to 2018. Methods This cross-sectional survey from...
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BMC
2024-01-01
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| Series: | BMC Public Health |
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| Online Access: | https://doi.org/10.1186/s12889-023-17619-y |
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| author | Ying Tian Dongna Li Haoliang Cui Xin Zhang Xiaoyan Fan Feng Lu |
| author_facet | Ying Tian Dongna Li Haoliang Cui Xin Zhang Xiaoyan Fan Feng Lu |
| author_sort | Ying Tian |
| collection | DOAJ |
| description | Abstract Background The multimorbidity of Atherosclerotic cardiovascular disease (ASCVD) and many other chronic conditions is becoming common. This study aimed to assess multimorbidity distribution in ASCVD among adults in the United States from 1999 to 2018. Methods This cross-sectional survey from the National Health and Nutrition Examination Survey (NHANES) 1999–2018 using stratified multistage probability design. Among the 53,083 survey respondents during the study period, 5,729 US adults aged ≥ 20 years with ASCVD. Joinpoint regression was used to assess the statistical significance of prevalence trends in the prevalence of ASCVD stratified by multimorbidity. The Apriori association rule mining algorithm was used to identify common multimorbidity association patterns in ASCVD patients. Results Overall, 5,729 of 53,083 individuals had ASCVD, and the prevalence showed a slow declining trend (biannual percentage change = -0.81%, p = 0.035, average 7.71%). The prevalence of ASCVD significantly decreased in populations without dyslipidemia, diabetes mellitus (DM), hypertension, asthma, chronic obstructive pulmonary disease (COPD), and arthritis (all groups, p < 0.05). Additionally, 65.6% of ASCVD patients had at least four of the 12 selected chronic conditions, with four and five being the most common numbers of conditions (17.9% and 17.7%, respectively). The five most common chronic conditions were (in order) dyslipidemia, hypertension, arthritis, chronic kidney disease, and DM. The coexistence of hypertension and dyslipidemia had the highest support in association rules (support = 0.63), while the coexistence of dyslipidemia, hypertension, metabolic syndrome, and DM had the highest lift (lift = 1.82). Conclusions During the 20-year survey period, there was a significant decrease in the overall prevalence of ASCVD. However, this reduction was primarily observed in individuals without dyslipidemia, DM, hypertension, asthma, COPD, and arthritis. Among populations with any of the evaluated chronic conditions, the prevalence of ASCVD remained unchanged. Most of ASCVD patients had four or more concurrent chronic conditions. |
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| issn | 1471-2458 |
| language | English |
| last_indexed | 2024-03-07T15:25:41Z |
| publishDate | 2024-01-01 |
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| series | BMC Public Health |
| spelling | doaj.art-60d9f921baed4ab38cf4f9ce0eb0e6642024-03-05T17:07:59ZengBMCBMC Public Health1471-24582024-01-0124111310.1186/s12889-023-17619-yEpidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018Ying Tian0Dongna Li1Haoliang Cui2Xin Zhang3Xiaoyan Fan4Feng Lu5Clinical Research Center, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Cardiology, Affiliated Hospital of Shandong University of Traditional Chinese MedicineSchool of Public Health, Peking UniversityClinical Research Center, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Cardiology, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Cardiology, Affiliated Hospital of Shandong University of Traditional Chinese MedicineAbstract Background The multimorbidity of Atherosclerotic cardiovascular disease (ASCVD) and many other chronic conditions is becoming common. This study aimed to assess multimorbidity distribution in ASCVD among adults in the United States from 1999 to 2018. Methods This cross-sectional survey from the National Health and Nutrition Examination Survey (NHANES) 1999–2018 using stratified multistage probability design. Among the 53,083 survey respondents during the study period, 5,729 US adults aged ≥ 20 years with ASCVD. Joinpoint regression was used to assess the statistical significance of prevalence trends in the prevalence of ASCVD stratified by multimorbidity. The Apriori association rule mining algorithm was used to identify common multimorbidity association patterns in ASCVD patients. Results Overall, 5,729 of 53,083 individuals had ASCVD, and the prevalence showed a slow declining trend (biannual percentage change = -0.81%, p = 0.035, average 7.71%). The prevalence of ASCVD significantly decreased in populations without dyslipidemia, diabetes mellitus (DM), hypertension, asthma, chronic obstructive pulmonary disease (COPD), and arthritis (all groups, p < 0.05). Additionally, 65.6% of ASCVD patients had at least four of the 12 selected chronic conditions, with four and five being the most common numbers of conditions (17.9% and 17.7%, respectively). The five most common chronic conditions were (in order) dyslipidemia, hypertension, arthritis, chronic kidney disease, and DM. The coexistence of hypertension and dyslipidemia had the highest support in association rules (support = 0.63), while the coexistence of dyslipidemia, hypertension, metabolic syndrome, and DM had the highest lift (lift = 1.82). Conclusions During the 20-year survey period, there was a significant decrease in the overall prevalence of ASCVD. However, this reduction was primarily observed in individuals without dyslipidemia, DM, hypertension, asthma, COPD, and arthritis. Among populations with any of the evaluated chronic conditions, the prevalence of ASCVD remained unchanged. Most of ASCVD patients had four or more concurrent chronic conditions.https://doi.org/10.1186/s12889-023-17619-yAtherosclerotic cardiovascular diseaseMultimorbidityNational Health and Nutrition Examination Survey |
| spellingShingle | Ying Tian Dongna Li Haoliang Cui Xin Zhang Xiaoyan Fan Feng Lu Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 BMC Public Health Atherosclerotic cardiovascular disease Multimorbidity National Health and Nutrition Examination Survey |
| title | Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 |
| title_full | Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 |
| title_fullStr | Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 |
| title_full_unstemmed | Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 |
| title_short | Epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the United States, 1999–2018 |
| title_sort | epidemiology of multimorbidity associated with atherosclerotic cardiovascular disease in the united states 1999 2018 |
| topic | Atherosclerotic cardiovascular disease Multimorbidity National Health and Nutrition Examination Survey |
| url | https://doi.org/10.1186/s12889-023-17619-y |
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