Harlequin color change in a premature infant: A case report

Key Clinical Message This case of HCC report contributes to the knowledge of HCC in China. In this case, the longer duration of the color change observed in this case compared to previous reports, which will be useful for all medical practitioners. Abstract Harlequin color change (HCC) is a benign s...

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Main Authors: Linzhi Yang, Guiying Zhuang, Dahu Zhang, Weiqi Liu
Format: Article
Language:English
Published: Wiley 2023-09-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.7840
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author Linzhi Yang
Guiying Zhuang
Dahu Zhang
Weiqi Liu
author_facet Linzhi Yang
Guiying Zhuang
Dahu Zhang
Weiqi Liu
author_sort Linzhi Yang
collection DOAJ
description Key Clinical Message This case of HCC report contributes to the knowledge of HCC in China. In this case, the longer duration of the color change observed in this case compared to previous reports, which will be useful for all medical practitioners. Abstract Harlequin color change (HCC) is a benign skin color change that lasts for a short time with no obvious physical abnormalities. Its pathogenesis is still unclear. It occurs in newborns, especially premature infants. However, few cases of HCC have been reported in China. Herein, we report a case of HCC. The infant was born at 34 + 4 weeks of gestation and was admitted to the hospital due to metabolic acidosis and neonatal pneumonia after birth. On the third day after birth, there were two red bands with obvious edges along the body centreline, and the erythema characteristics were consistent with those of HCC. The immature hypothalamus of newborns may cause the occurrence of HCC. At the same time, some drugs (midazolam), hypoxemia, and blood sampling may also be associated with HCC during neonatal hospitalization. All doctors should be thoroughly knowledgeable about the clinical characteristics of HCC and avoid using unnecessary drugs during treatment.
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spelling doaj.art-60daa4d42b9c41239874b41890ff7b142023-10-20T06:16:21ZengWileyClinical Case Reports2050-09042023-09-01119n/an/a10.1002/ccr3.7840Harlequin color change in a premature infant: A case reportLinzhi Yang0Guiying Zhuang1Dahu Zhang2Weiqi Liu3Department of Neonatology The Maternal and Children Health Care Hospital (Huzhong Hospital) of Huadu Guangzhou ChinaDepartment of Neonatology The Maternal and Children Health Care Hospital (Huzhong Hospital) of Huadu Guangzhou ChinaDepartment of Neonatology The Maternal and Children Health Care Hospital (Huzhong Hospital) of Huadu Guangzhou ChinaDepartment of Clinical Laboratory The Maternal and Children Health Care Hospital (Huzhong Hospital) of Huadu Guangzhou ChinaKey Clinical Message This case of HCC report contributes to the knowledge of HCC in China. In this case, the longer duration of the color change observed in this case compared to previous reports, which will be useful for all medical practitioners. Abstract Harlequin color change (HCC) is a benign skin color change that lasts for a short time with no obvious physical abnormalities. Its pathogenesis is still unclear. It occurs in newborns, especially premature infants. However, few cases of HCC have been reported in China. Herein, we report a case of HCC. The infant was born at 34 + 4 weeks of gestation and was admitted to the hospital due to metabolic acidosis and neonatal pneumonia after birth. On the third day after birth, there were two red bands with obvious edges along the body centreline, and the erythema characteristics were consistent with those of HCC. The immature hypothalamus of newborns may cause the occurrence of HCC. At the same time, some drugs (midazolam), hypoxemia, and blood sampling may also be associated with HCC during neonatal hospitalization. All doctors should be thoroughly knowledgeable about the clinical characteristics of HCC and avoid using unnecessary drugs during treatment.https://doi.org/10.1002/ccr3.7840blood extractioncompensatory acidosisharlequin color changemidazolamneonate
spellingShingle Linzhi Yang
Guiying Zhuang
Dahu Zhang
Weiqi Liu
Harlequin color change in a premature infant: A case report
Clinical Case Reports
blood extraction
compensatory acidosis
harlequin color change
midazolam
neonate
title Harlequin color change in a premature infant: A case report
title_full Harlequin color change in a premature infant: A case report
title_fullStr Harlequin color change in a premature infant: A case report
title_full_unstemmed Harlequin color change in a premature infant: A case report
title_short Harlequin color change in a premature infant: A case report
title_sort harlequin color change in a premature infant a case report
topic blood extraction
compensatory acidosis
harlequin color change
midazolam
neonate
url https://doi.org/10.1002/ccr3.7840
work_keys_str_mv AT linzhiyang harlequincolorchangeinaprematureinfantacasereport
AT guiyingzhuang harlequincolorchangeinaprematureinfantacasereport
AT dahuzhang harlequincolorchangeinaprematureinfantacasereport
AT weiqiliu harlequincolorchangeinaprematureinfantacasereport