Visualizing Influenza A Virus vRNA Replication

Influenza A virus (IAV) has caused recurrent epidemics and severe pandemics. In this study, we adapted an MS2-MCP live-cell imaging system to visualize IAV replication. A reporter plasmid, pHH-PB2-vMSL, was constructed by replacing a part of the PB2-coding sequence in pHH-PB2 with a sequence encodin...

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Bibliographic Details
Main Authors: Ya-Fang Chiu, Yi-Wen Huang, Chi-Yuan Chen, Yu-Chia Chen, Yu-Nong Gong, Rei-Lin Kuo, Chung-Guei Huang, Shin-Ru Shih
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.812711/full