Towards a single-assay approach: a combined DNA/RNA sequencing panel eliminates diagnostic redundancy and detects clinically-relevant fusions in neuropathology

Towards a single-assay approach: a combined DNA/RNA sequencing panel eliminates diagnostic redundancy and detects clinically-relevant fusions in neuropathology

Abstract Since the introduction of integrated histological and molecular diagnoses by the 2016 World Health Organization (WHO) Classification of Tumors of the Nervous System, an increasing number of molecular markers have been found to have prognostic significance in infiltrating gliomas, many of wh...

Full description

Bibliographic Details
Main Authors: Cheyanne C. Slocum, Hyeon Jin Park, Inji Baek, Jeff Catalano, Martin T. Wells, Benjamin Liechty, Susan Mathew, Wei Song, James P. Solomon, David J. Pisapia
Format: Article
Language:English
Published: BMC 2022-11-01
Series:Acta Neuropathologica Communications
Subjects:
CNS neoplasms
Next-generation sequencing
Molecular diagnostics
Online Access:https://doi.org/10.1186/s40478-022-01466-w

Similar Items

Similar Items