Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada
A multivariate spectrophotometric method was developed for analysis of kojic acid/hydroquinone associations in skin whitening cosmetics. The method is based on the reaction between kojic acid and Fe3+ and on the reduction of Fe3+ by hydroquinone and further complexation of Fe2+ with 1,10-phenanthrol...
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| Format: | Article |
| Language: | English |
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Sociedade Brasileira de Química
2011-01-01
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| Series: | Química Nova |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000400015&lng=en&tlng=en |
| _version_ | 1819154113368162304 |
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| author | Giselle Nathaly Calaça Sandra Stets Noemi Nagata |
| author_facet | Giselle Nathaly Calaça Sandra Stets Noemi Nagata |
| author_sort | Giselle Nathaly Calaça |
| collection | DOAJ |
| description | A multivariate spectrophotometric method was developed for analysis of kojic acid/hydroquinone associations in skin whitening cosmetics. The method is based on the reaction between kojic acid and Fe3+ and on the reduction of Fe3+ by hydroquinone and further complexation of Fe2+ with 1,10-phenanthroline. The multivariate model was developed by Partial Least Squares Regression (PLSR), using 25 synthetic mixtures and mean-centered spectral data (350-380 nm). The use of 3 (kojic acid) and 2 (hydroquinone) latent variables permits the observation of mean errors of about 5% in the external validation phase. |
| first_indexed | 2024-12-22T15:15:55Z |
| format | Article |
| id | doaj.art-60df7f162bbc41d3873dac6a5a24dbdc |
| institution | Directory Open Access Journal |
| issn | 1678-7064 |
| language | English |
| last_indexed | 2024-12-22T15:15:55Z |
| publishDate | 2011-01-01 |
| publisher | Sociedade Brasileira de Química |
| record_format | Article |
| series | Química Nova |
| spelling | doaj.art-60df7f162bbc41d3873dac6a5a24dbdc2022-12-21T18:21:46ZengSociedade Brasileira de QuímicaQuímica Nova1678-70642011-01-0134463063510.1590/S0100-40422011000400015S0100-40422011000400015Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariadaGiselle Nathaly Calaça0Sandra Stets1Noemi Nagata2Universidade Estadual de Ponta GrossaUniversidade Federal do ParanáUniversidade Federal do ParanáA multivariate spectrophotometric method was developed for analysis of kojic acid/hydroquinone associations in skin whitening cosmetics. The method is based on the reaction between kojic acid and Fe3+ and on the reduction of Fe3+ by hydroquinone and further complexation of Fe2+ with 1,10-phenanthroline. The multivariate model was developed by Partial Least Squares Regression (PLSR), using 25 synthetic mixtures and mean-centered spectral data (350-380 nm). The use of 3 (kojic acid) and 2 (hydroquinone) latent variables permits the observation of mean errors of about 5% in the external validation phase.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000400015&lng=en&tlng=enkojic acidhydroquinonevisible spectrophotometry |
| spellingShingle | Giselle Nathaly Calaça Sandra Stets Noemi Nagata Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada Química Nova kojic acid hydroquinone visible spectrophotometry |
| title | Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada |
| title_full | Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada |
| title_fullStr | Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada |
| title_full_unstemmed | Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada |
| title_short | Determinação simultânea de ácido kójico e hidroquinona por espectrofotometria visível e calibração multivariada |
| title_sort | determinacao simultanea de acido kojico e hidroquinona por espectrofotometria visivel e calibracao multivariada |
| topic | kojic acid hydroquinone visible spectrophotometry |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000400015&lng=en&tlng=en |
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