Role of VEGF-VEGFR2 signaling pathway in psoriasis

Role of VEGF-VEGFR2 signaling pathway in psoriasis

VEGF-VEGFR2 signaling pathway plays an important role in the course of psoriasis. Binding of VEGF to VEGFR2 induces receptor dimerization and autophosphorylation at multiple tyrosine sites, promoting the activation of the downstream ERK1/2 signaling pathway. Phosphorylated ERK1/2 is highly expressed...

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Bibliographic Details
Main Authors: Xiaomei LUO, Zhiyong CHENG, Xiaoqun HAN, Yong WANG
Format: Article
Language:zho
Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2022-10-01
Series:Pifu-xingbing zhenliaoxue zazhi
Subjects:
psoriasis
vegf-vegfr2 signaling pathway
Online Access:http://pfxbzlx.gdvdc.com/CN/10.3969/j.issn.1674-8468.2022.05.018

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