ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age
Among older people, a big problem is the decrease in both muscle strength and general physical fitness. This often prevents the proper functioning of a person, which makes him or her dependent on their guardians or family. It is believed that the ACE gene is associated with better results achieved i...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kazimierz Wielki University
2018-08-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5811 |
| _version_ | 1818332933776211968 |
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| author | Anna Marciniak Sylwester Kłoska Marcin Woźniak Radosław Perkowski Marta Podhorecka Dominika Gębka Joanna Androsiuk-Perkowska Henryk Kozłowski Kornelia Kędziora-Kornatowska Walery Zukow |
| author_facet | Anna Marciniak Sylwester Kłoska Marcin Woźniak Radosław Perkowski Marta Podhorecka Dominika Gębka Joanna Androsiuk-Perkowska Henryk Kozłowski Kornelia Kędziora-Kornatowska Walery Zukow |
| author_sort | Anna Marciniak |
| collection | DOAJ |
| description | Among older people, a big problem is the decrease in both muscle strength and general physical fitness. This often prevents the proper functioning of a person, which makes him or her dependent on their guardians or family. It is believed that the ACE gene is associated with better results achieved in strength sports. It may also be related to the health condition of older people. For this purpose, a study was conducted on a group of 60 people over 60 years of age. The study was conducted with the consent of the bioethical commission and under the supervision of physiotherapists. The relationship between overall fitness and muscle strength of older people with ACE genotypic variants was checked. For this purpose, a questionnaire on physical activity of IPAQ was used. On its basis, the values of MET and BMI coefficients were determined. Fitness tests were also carried out, i.e. SPPB, DGI and Up & Go. The ACE gene was tested by PCR. The insertion-deletion polymorphism of the Alu sequence in this gene was examined. It was found that: DD gene genotype ACE is associated with higher values of BMI and shorter standing time on the left leg (p |
| first_indexed | 2024-12-13T13:43:37Z |
| format | Article |
| id | doaj.art-60e11d560dd54ff4b73fcd967860a14d |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-12-13T13:43:37Z |
| publishDate | 2018-08-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-60e11d560dd54ff4b73fcd967860a14d2022-12-21T23:43:31ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062018-08-018914615410.5281/zenodo.13452245325ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of ageAnna Marciniak0Sylwester Kłoska1Marcin Woźniak2Radosław Perkowski3Marta Podhorecka4Dominika Gębka5Joanna Androsiuk-Perkowska6Henryk Kozłowski7Kornelia Kędziora-Kornatowska8Walery Zukow9Faculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Medicine, Institute of Molecular and Forensic Genetics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńFaculty of Health Sciences, Department and Clinic of Geriatrics, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University ToruńDepartment of Spatial Management and Tourism, Faculty of Earth Sciences, Nicolaus Copernicus University in Torun, TorunAmong older people, a big problem is the decrease in both muscle strength and general physical fitness. This often prevents the proper functioning of a person, which makes him or her dependent on their guardians or family. It is believed that the ACE gene is associated with better results achieved in strength sports. It may also be related to the health condition of older people. For this purpose, a study was conducted on a group of 60 people over 60 years of age. The study was conducted with the consent of the bioethical commission and under the supervision of physiotherapists. The relationship between overall fitness and muscle strength of older people with ACE genotypic variants was checked. For this purpose, a questionnaire on physical activity of IPAQ was used. On its basis, the values of MET and BMI coefficients were determined. Fitness tests were also carried out, i.e. SPPB, DGI and Up & Go. The ACE gene was tested by PCR. The insertion-deletion polymorphism of the Alu sequence in this gene was examined. It was found that: DD gene genotype ACE is associated with higher values of BMI and shorter standing time on the left leg (phttp://www.ojs.ukw.edu.pl/index.php/johs/article/view/5811aceolder adultsphysical performance testssport genetics |
| spellingShingle | Anna Marciniak Sylwester Kłoska Marcin Woźniak Radosław Perkowski Marta Podhorecka Dominika Gębka Joanna Androsiuk-Perkowska Henryk Kozłowski Kornelia Kędziora-Kornatowska Walery Zukow ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age Journal of Education, Health and Sport ace older adults physical performance tests sport genetics |
| title | ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| title_full | ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| title_fullStr | ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| title_full_unstemmed | ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| title_short | ACE I/D polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| title_sort | ace i d polymorphism associated with muscle strength and its relation to the health status of people over 60 years of age |
| topic | ace older adults physical performance tests sport genetics |
| url | http://www.ojs.ukw.edu.pl/index.php/johs/article/view/5811 |
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