Sec22b-dependent antigen cross-presentation is a significant contributor of T cell priming during infection with the parasite Trypanosoma cruzi

Sec22b-dependent antigen cross-presentation is a significant contributor of T cell priming during infection with the parasite Trypanosoma cruzi

Antigen cross-presentation is a vital mechanism of dendritic cells and other antigen presenting cells to orchestrate the priming of cytotoxic responses towards killing of infected or cancer cells. In this process, exogenous antigens are internalized by dendritic cells, processed, loaded onto MHC cla...

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Bibliographic Details
Main Authors:	Lucía Biscari, Ma Carmen Maza, Cecilia Farré, Cintia Daniela Kaufman, Sebastian Amigorena, Manuel Fresno, Núria Gironès, Andrés Alloatti
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-03-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	Sec22b SNARE protein antigen cross-presentation Trypanosoma cruzi dendritic cells CD8 + T cells cre-loxp transgenic mice
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1138571/full

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