I-KappaB Expression in Patient with Psoriasis Vulgaris

The goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surfa...

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Main Authors: Nahed Abdelazeem, Abdelaziz El Refaiee, Shimaa Othman
Format: Article
Language:English
Published: Beni-Suef University, Faculty of Medicine 2022-04-01
Series:Egyptian Journal of Medical Research
Subjects:
Online Access:https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdf
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author Nahed Abdelazeem
Abdelaziz El Refaiee
Shimaa Othman
author_facet Nahed Abdelazeem
Abdelaziz El Refaiee
Shimaa Othman
author_sort Nahed Abdelazeem
collection DOAJ
description The goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surface Index (PASI) score and serum samples for all participants were taken to measure I Kappa B level for each. The level of serum I Kappa B was found to be significantly lower in the patients (3.96 ±1.96)  than in controls (11.02 ±2.22). This difference was of statistical significance (p-value =0.001).
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spelling doaj.art-60e46c2804bc442eab1576ada4236e872023-02-27T17:41:48ZengBeni-Suef University, Faculty of MedicineEgyptian Journal of Medical Research2682-43962682-440X2022-04-013272210.21608/ejmr.2022.231672231672I-KappaB Expression in Patient with Psoriasis VulgarisNahed Abdelazeem0Abdelaziz El Refaiee1Shimaa Othman2Dermatology department, Faculty of Medicine, Cairo University, EgyptDermatology department, Faculty of Medicine, Beni-Suef University, EgyptDermatology department, Faculty of Medicine, Beni-Suef University, EgyptThe goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surface Index (PASI) score and serum samples for all participants were taken to measure I Kappa B level for each. The level of serum I Kappa B was found to be significantly lower in the patients (3.96 ±1.96)  than in controls (11.02 ±2.22). This difference was of statistical significance (p-value =0.001).https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdfpsoriasisi kappa b and nf-kb
spellingShingle Nahed Abdelazeem
Abdelaziz El Refaiee
Shimaa Othman
I-KappaB Expression in Patient with Psoriasis Vulgaris
Egyptian Journal of Medical Research
psoriasis
i kappa b and nf-kb
title I-KappaB Expression in Patient with Psoriasis Vulgaris
title_full I-KappaB Expression in Patient with Psoriasis Vulgaris
title_fullStr I-KappaB Expression in Patient with Psoriasis Vulgaris
title_full_unstemmed I-KappaB Expression in Patient with Psoriasis Vulgaris
title_short I-KappaB Expression in Patient with Psoriasis Vulgaris
title_sort i kappab expression in patient with psoriasis vulgaris
topic psoriasis
i kappa b and nf-kb
url https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdf
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