I-KappaB Expression in Patient with Psoriasis Vulgaris
The goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surfa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
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Beni-Suef University, Faculty of Medicine
2022-04-01
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Series: | Egyptian Journal of Medical Research |
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Online Access: | https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdf |
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author | Nahed Abdelazeem Abdelaziz El Refaiee Shimaa Othman |
author_facet | Nahed Abdelazeem Abdelaziz El Refaiee Shimaa Othman |
author_sort | Nahed Abdelazeem |
collection | DOAJ |
description | The goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surface Index (PASI) score and serum samples for all participants were taken to measure I Kappa B level for each. The level of serum I Kappa B was found to be significantly lower in the patients (3.96 ±1.96) than in controls (11.02 ±2.22). This difference was of statistical significance (p-value =0.001). |
first_indexed | 2024-04-10T07:01:40Z |
format | Article |
id | doaj.art-60e46c2804bc442eab1576ada4236e87 |
institution | Directory Open Access Journal |
issn | 2682-4396 2682-440X |
language | English |
last_indexed | 2024-04-10T07:01:40Z |
publishDate | 2022-04-01 |
publisher | Beni-Suef University, Faculty of Medicine |
record_format | Article |
series | Egyptian Journal of Medical Research |
spelling | doaj.art-60e46c2804bc442eab1576ada4236e872023-02-27T17:41:48ZengBeni-Suef University, Faculty of MedicineEgyptian Journal of Medical Research2682-43962682-440X2022-04-013272210.21608/ejmr.2022.231672231672I-KappaB Expression in Patient with Psoriasis VulgarisNahed Abdelazeem0Abdelaziz El Refaiee1Shimaa Othman2Dermatology department, Faculty of Medicine, Cairo University, EgyptDermatology department, Faculty of Medicine, Beni-Suef University, EgyptDermatology department, Faculty of Medicine, Beni-Suef University, EgyptThe goal of this study is to measure serum level of I Kappa B in patients with psoriasis in comparison with healthy controls. 50 psoriatic patients and 40 age & gender matched apparently healthy controls were included in the study, patients were classified according to Psoriasis Area & Surface Index (PASI) score and serum samples for all participants were taken to measure I Kappa B level for each. The level of serum I Kappa B was found to be significantly lower in the patients (3.96 ±1.96) than in controls (11.02 ±2.22). This difference was of statistical significance (p-value =0.001).https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdfpsoriasisi kappa b and nf-kb |
spellingShingle | Nahed Abdelazeem Abdelaziz El Refaiee Shimaa Othman I-KappaB Expression in Patient with Psoriasis Vulgaris Egyptian Journal of Medical Research psoriasis i kappa b and nf-kb |
title | I-KappaB Expression in Patient with Psoriasis Vulgaris |
title_full | I-KappaB Expression in Patient with Psoriasis Vulgaris |
title_fullStr | I-KappaB Expression in Patient with Psoriasis Vulgaris |
title_full_unstemmed | I-KappaB Expression in Patient with Psoriasis Vulgaris |
title_short | I-KappaB Expression in Patient with Psoriasis Vulgaris |
title_sort | i kappab expression in patient with psoriasis vulgaris |
topic | psoriasis i kappa b and nf-kb |
url | https://ejmr.journals.ekb.eg/article_231672_887180b2d54e2952b82669539368ac1d.pdf |
work_keys_str_mv | AT nahedabdelazeem ikappabexpressioninpatientwithpsoriasisvulgaris AT abdelazizelrefaiee ikappabexpressioninpatientwithpsoriasisvulgaris AT shimaaothman ikappabexpressioninpatientwithpsoriasisvulgaris |