Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy
Abstract Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-02-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-83143-x |
| _version_ | 1818424907830132736 |
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| author | Dong Sup Lee Seung-ju Lee |
| author_facet | Dong Sup Lee Seung-ju Lee |
| author_sort | Dong Sup Lee |
| collection | DOAJ |
| description | Abstract Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB. |
| first_indexed | 2024-12-14T14:05:30Z |
| format | Article |
| id | doaj.art-60e641a8cccd4877a3f2f12d5319a742 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-14T14:05:30Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-60e641a8cccd4877a3f2f12d5319a7422022-12-21T22:58:34ZengNature PortfolioScientific Reports2045-23222021-02-011111810.1038/s41598-021-83143-xUrodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomyDong Sup Lee0Seung-ju Lee1Department of Urology, St. Vincent’s Hospital, The Catholic University of Korea, College of MedicineDepartment of Urology, St. Vincent’s Hospital, The Catholic University of Korea, College of MedicineAbstract Radical prostatectomy can alter the anatomy of the urinary bladder. We aimed to evaluate bladder function before and 4 months after radical prostatectomy using the urodynamic test and overactive bladder (OAB) symptom score. Among 70 prospectively enrolled patients, 61 patients completed the study. In the urodynamic test, bladder capacity and compliance did not change, the frequency of involuntary detrusor contraction decreased, the maximum flow rate and bladder outlet obstruction index improved, and the maximum urethral closure pressure (MUCP) deteriorated. Further evaluation of urodynamic parameters according to changes in symptoms was made. Although change in bladder compliance was correlated with changes in OAB symptoms, not the relative change of bladder compliance but the relative change in the MUCP was reliable factor when OAB symptoms were deteriorated. In general, prostatectomy did not deteriorate the condition of the detrusor; rather, change in the MUCP could be responsible for postprostatectomy OAB.https://doi.org/10.1038/s41598-021-83143-x |
| spellingShingle | Dong Sup Lee Seung-ju Lee Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy Scientific Reports |
| title | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| title_full | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| title_fullStr | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| title_full_unstemmed | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| title_short | Urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| title_sort | urodynamic evaluation of patients with localized prostate cancer before and 4 months after robotic radical prostatectomy |
| url | https://doi.org/10.1038/s41598-021-83143-x |
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