Dieckol, a Major Marine Polyphenol, Enhances Non-Rapid Eye Movement Sleep in Mice via the GABAA-Benzodiazepine Receptor

Dieckol, a Major Marine Polyphenol, Enhances Non-Rapid Eye Movement Sleep in Mice via the GABAA-Benzodiazepine Receptor

We had previously demonstrated that phlorotannins, which are marine polyphenols, enhance sleep in mice via the GABAA-benzodiazepine (BZD) receptor. Among the constituents of phlorotannin, dieckol is a major marine polyphenol from the brown alga Ecklonia cava. Although phlorotannins are known to exer...

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Bibliographic Details
Main Authors: Minseok Yoon, Jin-Soo Kim, Sangwoo Seo, Kiwon Lee, Min Young Um, Jaekwang Lee, Jonghoon Jung, Suengmok Cho
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Pharmacology
Subjects:
dieckol
phlorotannins
marine polyphenols
sleep
electroencephalogram
hypnotic
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00494/full

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