Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data
Abstract Background Effectively managing the coexistence of both diabetes and disability necessitates substantial effort. Whether disability onset affects adherence to type 2 diabetes medication remains unclear. This study investigated whether disability onset reduces such adherence and whether any...
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| Format: | Article |
| Language: | English |
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BMC
2024-03-01
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| Series: | BMC Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12916-024-03324-z |
| _version_ | 1797266767864659968 |
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| author | Szu-Han Chen Miaw-Chwen Lee Christy Pu |
| author_facet | Szu-Han Chen Miaw-Chwen Lee Christy Pu |
| author_sort | Szu-Han Chen |
| collection | DOAJ |
| description | Abstract Background Effectively managing the coexistence of both diabetes and disability necessitates substantial effort. Whether disability onset affects adherence to type 2 diabetes medication remains unclear. This study investigated whether disability onset reduces such adherence and whether any reduction varies by disability type. Methods This study used the National Disability Registry and National Health Insurance Research Database from Taiwan to identify patients with type 2 diabetes who subsequently developed a disability from 2013 to 2020; these patients were matched with patients with type 2 diabetes without disability onset during the study period. Type 2 diabetes medication adherence was measured using the medication possession ratio (MPR). A difference-in-differences analysis was performed to determine the effect of disability onset on the MPR. Results The difference-in-differences analysis revealed that disability onset caused a reduction of 5.76% in the 1-year MPR (P < 0.001) and 13.21% in the 2-year MPR (P < 0.001). Among all disability types, organ disabilities, multiple disabilities, rare diseases, and a persistent vegetative state exhibited the largest reductions in 2-year MPR. Conclusions Policies aimed at improving medication adherence in individuals with disabilities should consider not only the specific disability type but also the distinct challenges and barriers these patients encounter in maintaining medication adherence. |
| first_indexed | 2024-04-25T01:05:56Z |
| format | Article |
| id | doaj.art-60e992364a664a0e875102f6a0ca2380 |
| institution | Directory Open Access Journal |
| issn | 1741-7015 |
| language | English |
| last_indexed | 2024-04-25T01:05:56Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Medicine |
| spelling | doaj.art-60e992364a664a0e875102f6a0ca23802024-03-10T12:14:32ZengBMCBMC Medicine1741-70152024-03-012211910.1186/s12916-024-03324-zMedication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide dataSzu-Han Chen0Miaw-Chwen Lee1Christy Pu2Department of Medicine, College of Medicine, National Yang Ming Chiao Tung UniversityDepartment of Social Welfare, National Chung Cheng UniversityInstitute of Public Health, College of Medicine, National Yang Ming Chiao Tung UniversityAbstract Background Effectively managing the coexistence of both diabetes and disability necessitates substantial effort. Whether disability onset affects adherence to type 2 diabetes medication remains unclear. This study investigated whether disability onset reduces such adherence and whether any reduction varies by disability type. Methods This study used the National Disability Registry and National Health Insurance Research Database from Taiwan to identify patients with type 2 diabetes who subsequently developed a disability from 2013 to 2020; these patients were matched with patients with type 2 diabetes without disability onset during the study period. Type 2 diabetes medication adherence was measured using the medication possession ratio (MPR). A difference-in-differences analysis was performed to determine the effect of disability onset on the MPR. Results The difference-in-differences analysis revealed that disability onset caused a reduction of 5.76% in the 1-year MPR (P < 0.001) and 13.21% in the 2-year MPR (P < 0.001). Among all disability types, organ disabilities, multiple disabilities, rare diseases, and a persistent vegetative state exhibited the largest reductions in 2-year MPR. Conclusions Policies aimed at improving medication adherence in individuals with disabilities should consider not only the specific disability type but also the distinct challenges and barriers these patients encounter in maintaining medication adherence.https://doi.org/10.1186/s12916-024-03324-zMedication possession ratioMedication adherenceDisabilityType 2 diabetes |
| spellingShingle | Szu-Han Chen Miaw-Chwen Lee Christy Pu Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data BMC Medicine Medication possession ratio Medication adherence Disability Type 2 diabetes |
| title | Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data |
| title_full | Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data |
| title_fullStr | Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data |
| title_full_unstemmed | Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data |
| title_short | Medication adherence in patients with type 2 diabetes after disability onset: a difference-in-differences analysis using nationwide data |
| title_sort | medication adherence in patients with type 2 diabetes after disability onset a difference in differences analysis using nationwide data |
| topic | Medication possession ratio Medication adherence Disability Type 2 diabetes |
| url | https://doi.org/10.1186/s12916-024-03324-z |
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