Evaluation of linagliptin dissolution from tablets using HPLC and UV methods

Linagliptin (LGT) is used to reduce glucose blood levels in patients with type 2 Diabetes mellitus. The proposed conditions for a biowaiver guide can be applied due to high solubility of linagliptin in aqueous media. The aim of the present study was to develop and validate a dissolution test for 5...

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Bibliographic Details
Main Authors: Rita Elena de Abreu Engel, Amanda Thomas Barden, Sarah Chagas Campanharo, Natália Olegário, Nadia Maria Volpato, Elfrides Eva Scherman Schapoval
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2019-12-01
Series:Drug Analytical Research
Online Access:https://seer.ufrgs.br/index.php/produto&producao/ojs/index.php/dar/article/view/97847