Replication Origin Deletion Enhances Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Synthesis in Haloarchaea

Replication Origin Deletion Enhances Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Synthesis in Haloarchaea

ABSTRACT Although the use of multiple replication origins for chromosome replication has been widely characterized in haloarchaea, whether it is possible to manipulate the chromosome copy number by their genetic engineering is not known, and how it would affect the cell functioning is poorly underst...

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Bibliographic Details
Main Authors: Haibo Yang, Junyu Chen, Ruchira Mitra, Qiong Xue, Hua Xiang, Jing Han
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
haloarchaea
active replication origin
polyploidy
copy number
chromosome
megaplasmid
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02149-22

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