The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention
Background/objectivesMaternal illicit drug use is associated with negative physical and developmental outcomes for their born children. We aim to find out the incidence of different developmental problems in a cohort of Chinese children born to drug-abusing mothers, compare the physical health and d...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-10-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2022.1004890/full |
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| author | Anna Wai Fun Cheng Hin Biu Chan Lai Sheung Ip Katy Kit Ying Wan Ellen Lok Man Yu Wa Keung Chiu Pui Hong Chung Eng Kiong Yeoh |
| author_facet | Anna Wai Fun Cheng Hin Biu Chan Lai Sheung Ip Katy Kit Ying Wan Ellen Lok Man Yu Wa Keung Chiu Pui Hong Chung Eng Kiong Yeoh |
| author_sort | Anna Wai Fun Cheng |
| collection | DOAJ |
| description | Background/objectivesMaternal illicit drug use is associated with negative physical and developmental outcomes for their born children. We aim to find out the incidence of different developmental problems in a cohort of Chinese children born to drug-abusing mothers, compare the physical health and developmental outcomes of the subjects recruited in the Integrated Program to the Comprehensive Child Development Service (CCDS), and to study the potential factors on their associations.MethodsA retrospective longitudinal cohort study with frequent clinical assessments of the children’s physical and developmental outcomes in a HKSAR’s regional hospital from birth until 5 years old. 123 Children in Integrated Program were compared with 214 children in CCDS between 1 January 2008 and 28 February 2019. Cox regression analysis was performed to determine the possible factors associated with the developmental outcomes.ResultsDevelopmental delay was detected in 129 children (38.9%). CCDS group has significantly higher incidence of cognitive delay (p = < 0.001), language delay (p = < 0.001), motor delay (p = < 0.001), social delay (p = 0.002), and global delay (p = 0.002). On Cox multivariable regression analysis, integrated program (HRadj 0.53, 95% C. I. 0.34–0.84), social support (HRadj 0.45, 95% C.I. 0.25–0.80), and maternal abstinence from drug use up to 2-year post-delivery (HRadj 0.62, 95% C.I. 0.40–0.95) were significant protective factors, while male gender (HRadj 1.73, 95% C.I. 1.18–2.54) was a significant risk factor.ConclusionCCDS achieves early engagement of drug-abusing expectant mothers during pregnancy, and an early integrated program with multidisciplinary collaboration was an independent factor in improving the developmental outcomes of these vulnerable children. |
| first_indexed | 2024-04-11T18:58:29Z |
| format | Article |
| id | doaj.art-60f732ea140e4a09941feb6498b2c661 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-04-11T18:58:29Z |
| publishDate | 2022-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-60f732ea140e4a09941feb6498b2c6612022-12-22T04:08:06ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602022-10-011010.3389/fped.2022.10048901004890The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early interventionAnna Wai Fun Cheng0Hin Biu Chan1Lai Sheung Ip2Katy Kit Ying Wan3Ellen Lok Man Yu4Wa Keung Chiu5Pui Hong Chung6Eng Kiong Yeoh7Department of Pediatrics and Adolescent Medicine, United Christian Hospital, Hong Kong, Hong Kong SAR, ChinaDepartment of Pediatrics and Adolescent Medicine, United Christian Hospital, Hong Kong, Hong Kong SAR, ChinaDepartment of Obstetrics and Gynaecology, United Christian Hospital, Hong Kong, Hong Kong SAR, ChinaRainbow Lutheran Centre, Hong Kong Lutheran Social Service, Hong Kong, Hong Kong SAR, ChinaClinical Research Centre, Kowloon West Cluster, Hospital Authority, Hong Kong, Hong Kong SAR, ChinaDepartment of Pediatrics and Adolescent Medicine, United Christian Hospital, Hong Kong, Hong Kong SAR, ChinaCentre for Health Systems and Policy Research, The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, ChinaCentre for Health Systems and Policy Research, The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, ChinaBackground/objectivesMaternal illicit drug use is associated with negative physical and developmental outcomes for their born children. We aim to find out the incidence of different developmental problems in a cohort of Chinese children born to drug-abusing mothers, compare the physical health and developmental outcomes of the subjects recruited in the Integrated Program to the Comprehensive Child Development Service (CCDS), and to study the potential factors on their associations.MethodsA retrospective longitudinal cohort study with frequent clinical assessments of the children’s physical and developmental outcomes in a HKSAR’s regional hospital from birth until 5 years old. 123 Children in Integrated Program were compared with 214 children in CCDS between 1 January 2008 and 28 February 2019. Cox regression analysis was performed to determine the possible factors associated with the developmental outcomes.ResultsDevelopmental delay was detected in 129 children (38.9%). CCDS group has significantly higher incidence of cognitive delay (p = < 0.001), language delay (p = < 0.001), motor delay (p = < 0.001), social delay (p = 0.002), and global delay (p = 0.002). On Cox multivariable regression analysis, integrated program (HRadj 0.53, 95% C. I. 0.34–0.84), social support (HRadj 0.45, 95% C.I. 0.25–0.80), and maternal abstinence from drug use up to 2-year post-delivery (HRadj 0.62, 95% C.I. 0.40–0.95) were significant protective factors, while male gender (HRadj 1.73, 95% C.I. 1.18–2.54) was a significant risk factor.ConclusionCCDS achieves early engagement of drug-abusing expectant mothers during pregnancy, and an early integrated program with multidisciplinary collaboration was an independent factor in improving the developmental outcomes of these vulnerable children.https://www.frontiersin.org/articles/10.3389/fped.2022.1004890/fullmaternal substance abusephysical healthdevelopmental outcome0 to 5 years old childrenearly integrated programmultidisciplinary collaboration |
| spellingShingle | Anna Wai Fun Cheng Hin Biu Chan Lai Sheung Ip Katy Kit Ying Wan Ellen Lok Man Yu Wa Keung Chiu Pui Hong Chung Eng Kiong Yeoh The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention Frontiers in Pediatrics maternal substance abuse physical health developmental outcome 0 to 5 years old children early integrated program multidisciplinary collaboration |
| title | The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention |
| title_full | The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention |
| title_fullStr | The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention |
| title_full_unstemmed | The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention |
| title_short | The physical and developmental outcomes of children whose mothers are substance abusers: Analysis of associated factors and the impact of early intervention |
| title_sort | physical and developmental outcomes of children whose mothers are substance abusers analysis of associated factors and the impact of early intervention |
| topic | maternal substance abuse physical health developmental outcome 0 to 5 years old children early integrated program multidisciplinary collaboration |
| url | https://www.frontiersin.org/articles/10.3389/fped.2022.1004890/full |
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