Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs
Background The genetic landscape of the Qiongzhong aborigines, who reside in “the Heart of Hainan,” is still unclear. The Goldeneye™ DNA ID System 20 A is available for forensic and population genetics applications. Aim To obtain genetic polymorphisms of 19 autosomal STR loci in the Qiongzhong abori...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-05-01
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| Series: | Annals of Human Biology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/03014460.2021.1951352 |
| _version_ | 1797685169738481664 |
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| author | Fenfen Wang Zhengming Du Bingbing Han Shengping Cao Fangshu Fu Zhenming Luo Ziqing Mu Jirui Chen Pingming Qiu Haoliang Fan |
| author_facet | Fenfen Wang Zhengming Du Bingbing Han Shengping Cao Fangshu Fu Zhenming Luo Ziqing Mu Jirui Chen Pingming Qiu Haoliang Fan |
| author_sort | Fenfen Wang |
| collection | DOAJ |
| description | Background The genetic landscape of the Qiongzhong aborigines, who reside in “the Heart of Hainan,” is still unclear. The Goldeneye™ DNA ID System 20 A is available for forensic and population genetics applications. Aim To obtain genetic polymorphisms of 19 autosomal STR loci in the Qiongzhong aborigines, and to explore the genetic relationships with a total of 69,132 people from forty-five populations. Subjects and methods Genotype data on 19 autosomal STRs were collected from 724 Qiongzhong aborigines and phylogenetic relationships were conducted by multidimensional scaling analysis (MDS), principal component analysis (PCA) and neighbor-joining (N-J) phylogenetic tree construction. Results No evidence of deviation from Hardy-Weinberg equilibrium was identified. A total of 233 distinct alleles were observed with allele frequencies ranging from 0.0007 to 0.5375. The combined power of discrimination (CPD) and combined power of exclusion (CPE) for the 19 autosomal STR loci were 1–8.28 × 10–34 and 0.999999987, respectively. Conclusion Our phylogenetic results demonstrated that (a) the populations of Southeast Asian countries have thorough integrations with southern China in terms of ethnicity and genetics due to long-term cultural and trade exchanges, and (b) based on genetic and linguistic analysis, the Qiongzhong aborigines have a close relationship with Fujian Han Chinese.Highlights The STR landscape of Qiongzhong aborigines inhabited in Hainan tropical rainforests was depicted by 19 autosomal STRs. A total of 69,132 people from forty-five populations were selected for a more extensive examination of genetic similarities and differences by multivariate statistical methods (MDS, PCA and N-J tree construction). The genetic analyses indicated that the populations of Southeast Asian countries are very genetically close to southern Chinese populations. From the genetic and linguistic perspective, the Qiongzhong aborigines have a close relationship with Han Chinese from Fujian Province. |
| first_indexed | 2024-03-12T00:40:15Z |
| format | Article |
| id | doaj.art-60f87826d20c4c71be3e216eac829de0 |
| institution | Directory Open Access Journal |
| issn | 0301-4460 1464-5033 |
| language | English |
| last_indexed | 2024-03-12T00:40:15Z |
| publishDate | 2021-05-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Annals of Human Biology |
| spelling | doaj.art-60f87826d20c4c71be3e216eac829de02023-09-15T08:45:19ZengTaylor & Francis GroupAnnals of Human Biology0301-44601464-50332021-05-0148433534210.1080/03014460.2021.19513521951352Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRsFenfen Wang0Zhengming Du1Bingbing Han2Shengping Cao3Fangshu Fu4Zhenming Luo5Ziqing Mu6Jirui Chen7Pingming Qiu8Haoliang Fan9First Clinical Medical College, Hainan Medical UniversityFirst Clinical Medical College, Hainan Medical UniversitySchool of Traditional Chinese Medicine, Hainan Medical UniversityFirst Clinical Medical College, Hainan Medical UniversitySchool of Biomedical Information and Engineering, Hainan Medical UniversityFirst Clinical Medical College, Hainan Medical UniversitySchool of Management, Hainan Medical UniversityFirst Clinical Medical College, Hainan Medical UniversitySchool of Forensic Medicine, Southern Medical UniversityFirst Clinical Medical College, Hainan Medical UniversityBackground The genetic landscape of the Qiongzhong aborigines, who reside in “the Heart of Hainan,” is still unclear. The Goldeneye™ DNA ID System 20 A is available for forensic and population genetics applications. Aim To obtain genetic polymorphisms of 19 autosomal STR loci in the Qiongzhong aborigines, and to explore the genetic relationships with a total of 69,132 people from forty-five populations. Subjects and methods Genotype data on 19 autosomal STRs were collected from 724 Qiongzhong aborigines and phylogenetic relationships were conducted by multidimensional scaling analysis (MDS), principal component analysis (PCA) and neighbor-joining (N-J) phylogenetic tree construction. Results No evidence of deviation from Hardy-Weinberg equilibrium was identified. A total of 233 distinct alleles were observed with allele frequencies ranging from 0.0007 to 0.5375. The combined power of discrimination (CPD) and combined power of exclusion (CPE) for the 19 autosomal STR loci were 1–8.28 × 10–34 and 0.999999987, respectively. Conclusion Our phylogenetic results demonstrated that (a) the populations of Southeast Asian countries have thorough integrations with southern China in terms of ethnicity and genetics due to long-term cultural and trade exchanges, and (b) based on genetic and linguistic analysis, the Qiongzhong aborigines have a close relationship with Fujian Han Chinese.Highlights The STR landscape of Qiongzhong aborigines inhabited in Hainan tropical rainforests was depicted by 19 autosomal STRs. A total of 69,132 people from forty-five populations were selected for a more extensive examination of genetic similarities and differences by multivariate statistical methods (MDS, PCA and N-J tree construction). The genetic analyses indicated that the populations of Southeast Asian countries are very genetically close to southern Chinese populations. From the genetic and linguistic perspective, the Qiongzhong aborigines have a close relationship with Han Chinese from Fujian Province.http://dx.doi.org/10.1080/03014460.2021.1951352qiongzhong aboriginesstrgenetic diversityforensic characteristicphylogenetic analysis |
| spellingShingle | Fenfen Wang Zhengming Du Bingbing Han Shengping Cao Fangshu Fu Zhenming Luo Ziqing Mu Jirui Chen Pingming Qiu Haoliang Fan Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs Annals of Human Biology qiongzhong aborigines str genetic diversity forensic characteristic phylogenetic analysis |
| title | Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs |
| title_full | Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs |
| title_fullStr | Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs |
| title_full_unstemmed | Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs |
| title_short | Genetic diversity, forensic characteristics and phylogenetic analysis of the Qiongzhong aborigines residing in the tropical rainforests of Hainan Island via 19 autosomal STRs |
| title_sort | genetic diversity forensic characteristics and phylogenetic analysis of the qiongzhong aborigines residing in the tropical rainforests of hainan island via 19 autosomal strs |
| topic | qiongzhong aborigines str genetic diversity forensic characteristic phylogenetic analysis |
| url | http://dx.doi.org/10.1080/03014460.2021.1951352 |
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