Inhibitory Effect of Sauchinone on UDP-Glucuronosyltransferase (UGT) 2B7 Activity

Inhibitory Effect of Sauchinone on UDP-Glucuronosyltransferase (UGT) 2B7 Activity

Herb–drug interaction (HDI) limits clinical application of herbs and drugs, and inhibition of herbs towards uridine diphosphate (UDP)-glucuronosyltransferases (UGTs) has gained attention as one of the important reasons to cause HDIs. Sauchinone, an active lignan isolated from aerial parts of Saururu...

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Bibliographic Details
Main Authors: Byoung Hoon You, Eun Chae Gong, Young Hee Choi
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Molecules
Subjects:
sauchinone
Saururus chinensis
UGT2B7
inhibition
drug interaction
Online Access:http://www.mdpi.com/1420-3049/23/2/366

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