Integrin-β1, not integrin-β5, mediates osteoblastic differentiation and ECM formation promoted by mechanical tensile strain

Integrin-β1, not integrin-β5, mediates osteoblastic differentiation and ECM formation promoted by mechanical tensile strain

BACKGROUND: Mechanical strain plays a great role in growth and differentiation of osteoblast. A previous study indicated that integrin-β (β1, β5) mediated osteoblast proliferation promoted by mechanical tensile strain. However, the involvement of integrin-β in osteoblastic differentiation and extrac...

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Bibliographic Details
Main Authors: Qiangcheng Zeng, Yong Guo, Yongming Liu, Ruixin Li, Xinchang Zhang, Lu Liu, Yang Wang, Xizheng Zhang, Xianqiong Zou
Format: Article
Language:English
Published: BMC 2015-01-01
Series:Biological Research
Subjects:
Tensile strain
Osteoblast
Extracellular matrix
Integrin
siRNA
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602015000100025&lng=en&tlng=en

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