Trypanosoma cruzi antigen detection in blood to assess treatment efficacy and cure in mice models of Chagas disease

Trypanosoma cruzi antigen detection in blood to assess treatment efficacy and cure in mice models of Chagas disease

IntroductionChagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi. Although endemic mainly in Latin America, CD has become a global public health problem due to migration of infected individuals to non-endemic regions. Despite progress made in drug development, preclinical assays...

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Main Authors: Fernanda Fortes de Araujo, Rana Nagarkatti, Ana Lia Mazzeti, Karolina Ribeiro Gonçalves, Lívia de Figueiredo Diniz, Isabela Campos do Vale, Olindo Assis Martins-Filho, Alain Debrabant, Maria Terezinha Bahia, Andréa Teixeira-Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
Chagas disease
Trypanosoma cruzi
aptamer
treatment
efficacy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1340755/full

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