Thimet oligopeptidase as a potential CSF biomarker for Alzheimer's disease: A cross‐platform validation study

Abstract INTRODUCTION Our previous antibody‐based cerebrospinal fluid (CSF) proteomics study showed that Thimet oligopeptidase (THOP1), an amyloid beta (Aβ) neuropeptidase, was increased in mild cognitive impairment with amyloid pathology (MCI‐Aβ+) and Alzheimer's disease (AD) dementia compared...

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Main Authors: Yanaika S. Hok‐A‐Hin, Katharina Bolsewig, Daimy N. Ruiters, Alberto Lleó, Daniel Alcolea, Afina W. Lemstra, Wiesje M. van derFlier, Charlotte E. Teunissen, Marta delCampo
格式: 文件
语言:English
出版: Wiley 2023-07-01
丛编:Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
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在线阅读:https://doi.org/10.1002/dad2.12456