Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure
Background: Diabetes mellitus is associated with a theoretical increase in risk of development of post-operative infections; however, literature on the subject is conflicted, with some studies negating the effect of high blood sugar on the development of surgical wound si...
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Format: | Article |
Language: | English |
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Health Research Institute (HRI), National Institute of Health (NIH)
2023-05-01
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Series: | Pakistan Journal of Medical Research |
Subjects: | |
Online Access: | https://pjmr.org.pk/index.php/pjmr/article/view/416/136 |
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author | Rohan Qamar Khalid Mahmood Narisa Pervaiz Romassa Javed Faheem Sher Ibrahim Tufail |
author_facet | Rohan Qamar Khalid Mahmood Narisa Pervaiz Romassa Javed Faheem Sher Ibrahim Tufail |
author_sort | Rohan Qamar |
collection | DOAJ |
description | Background: Diabetes mellitus is associated with a theoretical increase in risk of development of post-operative infections; however, literature on the subject is conflicted, with some studies negating the effect of high blood sugar on the development of surgical wound site complications.Objectives: To compare the complications of ventral hernia repair in diabetics versus non-diabetics in terms of frequency of surgical site infection, seroma and haematoma formationStudy type,settings& duration:A prospective cohort study conducted Department of General Surgery, Combined Military Hospital,Rawalpindi from November 2019 to December2020.Methodology:Atotal of 182 patients (91 in each group) diagnosed with a ventral abdominal hernia who met the sample selection criteria were included. Patients who were diabetic were placed in Group A, while Group B patients were non-diabetic. All patients were followed up for surgical site infection, seroma and haematoma formation. Data was analyzed using SPSS 26.0.Results:The mean age of patients was 46.54±10.58 years (range 25-70 years). The patients included 113 females (62.1%) and 69 males (37.9%). A total of9 (9.9%) patients developed surgical site infections in Group A versus 2 (2.2%) in Group B, (p=0.029). Seroma formation was seen in 4 (4.4%) patients of Group A versus 2 (2.2%) Group B patients, p=0.406. One(1.1%) case from each group developed haematomas, (p=1.000).The relative riskratios in diabetics for developing surgical site infections, seromas and haematomas were RR: 4.9 (CI 95% 1.03 –23.3), RR: 2.1 (CI 95% 0.37 –11.5) and RR: 1.0 (CI 95% 0.06–16.2).Conclusion:Diabetics are prone to increased rates of surgical site infection, even in clean surgeries, when compared to non-diabetics, but there was no difference in frequencies of other complications. |
first_indexed | 2024-03-13T09:50:47Z |
format | Article |
id | doaj.art-610800f7db7f4e788cff3601290ceb34 |
institution | Directory Open Access Journal |
issn | 0030-9842 |
language | English |
last_indexed | 2024-03-13T09:50:47Z |
publishDate | 2023-05-01 |
publisher | Health Research Institute (HRI), National Institute of Health (NIH) |
record_format | Article |
series | Pakistan Journal of Medical Research |
spelling | doaj.art-610800f7db7f4e788cff3601290ceb342023-05-24T10:29:37ZengHealth Research Institute (HRI), National Institute of Health (NIH)Pakistan Journal of Medical Research0030-98422023-05-016211418Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical ProcedureRohan Qamar0Khalid Mahmood1Narisa Pervaiz2Romassa Javed3Faheem Sher4Ibrahim Tufail5Department of Surgery, Combined Military Hospital, Rawalpindi.Department of Surgery, Combined Military Hospital, Rawalpindi.Department of Surgery, Combined Military Hospital, Rawalpindi.Department of Surgery, Combined Military Hospital, Rawalpindi.Department of Surgery, Combined Military Hospital, Rawalpindi.Department of Surgery, Combined Military Hospital, Rawalpindi.Background: Diabetes mellitus is associated with a theoretical increase in risk of development of post-operative infections; however, literature on the subject is conflicted, with some studies negating the effect of high blood sugar on the development of surgical wound site complications.Objectives: To compare the complications of ventral hernia repair in diabetics versus non-diabetics in terms of frequency of surgical site infection, seroma and haematoma formationStudy type,settings& duration:A prospective cohort study conducted Department of General Surgery, Combined Military Hospital,Rawalpindi from November 2019 to December2020.Methodology:Atotal of 182 patients (91 in each group) diagnosed with a ventral abdominal hernia who met the sample selection criteria were included. Patients who were diabetic were placed in Group A, while Group B patients were non-diabetic. All patients were followed up for surgical site infection, seroma and haematoma formation. Data was analyzed using SPSS 26.0.Results:The mean age of patients was 46.54±10.58 years (range 25-70 years). The patients included 113 females (62.1%) and 69 males (37.9%). A total of9 (9.9%) patients developed surgical site infections in Group A versus 2 (2.2%) in Group B, (p=0.029). Seroma formation was seen in 4 (4.4%) patients of Group A versus 2 (2.2%) Group B patients, p=0.406. One(1.1%) case from each group developed haematomas, (p=1.000).The relative riskratios in diabetics for developing surgical site infections, seromas and haematomas were RR: 4.9 (CI 95% 1.03 –23.3), RR: 2.1 (CI 95% 0.37 –11.5) and RR: 1.0 (CI 95% 0.06–16.2).Conclusion:Diabetics are prone to increased rates of surgical site infection, even in clean surgeries, when compared to non-diabetics, but there was no difference in frequencies of other complications.https://pjmr.org.pk/index.php/pjmr/article/view/416/136diabetes mellitussurgical site infectionventral hernia repair |
spellingShingle | Rohan Qamar Khalid Mahmood Narisa Pervaiz Romassa Javed Faheem Sher Ibrahim Tufail Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure Pakistan Journal of Medical Research diabetes mellitus surgical site infection ventral hernia repair |
title | Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure |
title_full | Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure |
title_fullStr | Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure |
title_full_unstemmed | Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure |
title_short | Comparative Study on Incidence of Post-operative Wound Infection in Diabetic vs Non-diabetic Patients in Clean Surgical Procedure |
title_sort | comparative study on incidence of post operative wound infection in diabetic vs non diabetic patients in clean surgical procedure |
topic | diabetes mellitus surgical site infection ventral hernia repair |
url | https://pjmr.org.pk/index.php/pjmr/article/view/416/136 |
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