Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation
Abstract Multifocal contact lenses (MCLs) are one of the solutions to correct presbyopia, but their adoption is not widespread. To address this situation, visual simulators can be used to refine the adaptation process. This study aims to obtain accurate simulations for a visual simulator (SimVis Gek...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2024-04-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-59178-1 |
| _version_ | 1827284289256947712 |
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| author | Eduardo Esteban-Ibañez Diego Montagud-Martínez Lucie Sawides Amal Zaytouny Alberto de Castro Irene Sisó-Fuertes Xoana Barcala David P. Piñero Walter D. Furlan Carlos Dorronsoro Enrique Gambra |
| author_facet | Eduardo Esteban-Ibañez Diego Montagud-Martínez Lucie Sawides Amal Zaytouny Alberto de Castro Irene Sisó-Fuertes Xoana Barcala David P. Piñero Walter D. Furlan Carlos Dorronsoro Enrique Gambra |
| author_sort | Eduardo Esteban-Ibañez |
| collection | DOAJ |
| description | Abstract Multifocal contact lenses (MCLs) are one of the solutions to correct presbyopia, but their adoption is not widespread. To address this situation, visual simulators can be used to refine the adaptation process. This study aims to obtain accurate simulations for a visual simulator (SimVis Gekko; 2EyesVision) of daily soft MCL designs from four manufacturers. In-vitro characterization of these MCLs—several powers and additions- was obtained using NIMO TR-1504. From the averaged relative power profiles across powers, phase maps were reconstructed and the Through-Focus Visual Strehl metric was calculated for each MCL design. The SimVis Gekko simulation corresponding to each MCL design was obtained computationally and bench-validated. Finally, the MCL simulations were clinically validated involving presbyopic patients. The clinical validation results show a good agreement between the SimVis Gekko simulations and the real MCLs for through-focus visual acuity (TF-VA) curves and VA at three real distances. All MCL designs showed a partial correlation higher than 0.90 and a Root Mean Square Error below 0.07 logMAR between the TF-VA of simulations and Real MCLs across subjects. The validity of the simulation approach using SimVis Gekko and in-vitro measurements was confirmed in this study, opening the possibility to accelerate the adaptation of MCLs. |
| first_indexed | 2024-04-24T09:53:15Z |
| format | Article |
| id | doaj.art-61090291191a4192a04e42f6cf039ed6 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-04-24T09:53:15Z |
| publishDate | 2024-04-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-61090291191a4192a04e42f6cf039ed62024-04-14T11:15:46ZengNature PortfolioScientific Reports2045-23222024-04-0114111110.1038/s41598-024-59178-1Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validationEduardo Esteban-Ibañez0Diego Montagud-Martínez1Lucie Sawides2Amal Zaytouny3Alberto de Castro4Irene Sisó-Fuertes5Xoana Barcala6David P. Piñero7Walter D. Furlan8Carlos Dorronsoro9Enrique Gambra102EyesVision SLCentro de Tecnologías Físicas, Universitat Politècnica de València2EyesVision SLInstitute of Optics ‘Daza de Valdés’, Spanish National Research Council, IO-CSICInstitute of Optics ‘Daza de Valdés’, Spanish National Research Council, IO-CSIC2EyesVision SL2EyesVision SLDepartamento de Óptica, Farmacología y Anatomía, Universidad de AlicanteDepartamento de Óptica y Optometría y Ciencias de la Visión, Universitat de València2EyesVision SL2EyesVision SLAbstract Multifocal contact lenses (MCLs) are one of the solutions to correct presbyopia, but their adoption is not widespread. To address this situation, visual simulators can be used to refine the adaptation process. This study aims to obtain accurate simulations for a visual simulator (SimVis Gekko; 2EyesVision) of daily soft MCL designs from four manufacturers. In-vitro characterization of these MCLs—several powers and additions- was obtained using NIMO TR-1504. From the averaged relative power profiles across powers, phase maps were reconstructed and the Through-Focus Visual Strehl metric was calculated for each MCL design. The SimVis Gekko simulation corresponding to each MCL design was obtained computationally and bench-validated. Finally, the MCL simulations were clinically validated involving presbyopic patients. The clinical validation results show a good agreement between the SimVis Gekko simulations and the real MCLs for through-focus visual acuity (TF-VA) curves and VA at three real distances. All MCL designs showed a partial correlation higher than 0.90 and a Root Mean Square Error below 0.07 logMAR between the TF-VA of simulations and Real MCLs across subjects. The validity of the simulation approach using SimVis Gekko and in-vitro measurements was confirmed in this study, opening the possibility to accelerate the adaptation of MCLs.https://doi.org/10.1038/s41598-024-59178-1 |
| spellingShingle | Eduardo Esteban-Ibañez Diego Montagud-Martínez Lucie Sawides Amal Zaytouny Alberto de Castro Irene Sisó-Fuertes Xoana Barcala David P. Piñero Walter D. Furlan Carlos Dorronsoro Enrique Gambra Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation Scientific Reports |
| title | Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation |
| title_full | Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation |
| title_fullStr | Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation |
| title_full_unstemmed | Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation |
| title_short | Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation |
| title_sort | simulation of daily soft multifocal contact lenses using simvis gekko from in vitro and computational characterization to clinical validation |
| url | https://doi.org/10.1038/s41598-024-59178-1 |
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