MBD5 regulates NMDA receptor expression and seizures by inhibiting Stat1 transcription
Epilepsy is considered to result from an imbalance between excitation and inhibition of the central nervous system. Pathogenic mutations in the methyl-CpG binding domain protein 5 gene (MBD5) are known to cause epilepsy. However, the function and mechanism of MBD5 in epilepsy remain elusive. Here, w...
Main Authors: | Feng-lin Tang, Xiao-gang Zhang, Ping-yang Ke, Jie Liu, Zhi-juan Zhang, Dan-mei Hu, Juan Gu, Hui Zhang, Hao-kun Guo, Qian-wen Zang, Rui Huang, Yuan-lin Ma, Patrick Kwan |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-06-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996123001171 |
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