Venetoclax for Children and Adolescents with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Venetoclax for Children and Adolescents with Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma

Venetoclax is approved for adult patients with chronic lymphocytic leukemia and acute myeloid leukemia. Expanding its use to the pediatric population is currently under investigation, but more robust data are needed. We retrospectively analyzed the safety and efficacy of venetoclax in children/AYA w...

Full description

Bibliographic Details
Main Authors:	Amber Gibson, Adriana Trabal, David McCall, Sajad Khazal, Laurie Toepfer, Donna H. Bell, Michael Roth, Kris M. Mahadeo, Cesar Nunez, Nicholas J. Short, Courtney DiNardo, Marina Konopleva, Ghayas C. Issa, Farhad Ravandi, Nitin Jain, Gautam Borthakur, Hagop M. Kantarjian, Elias Jabbour, Branko Cuglievan
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Series:	Cancers
Subjects:	acute lymphoblastic leukemia lymphoblastic lymphoma venetoclax Bcl-2 inhibitor early precursor T-cell
Online Access:	https://www.mdpi.com/2072-6694/14/1/150

Similar Items

Combined Application of Pan-AKT Inhibitor MK-2206 and BCL-2 Antagonist Venetoclax in B-Cell Precursor Acute Lymphoblastic Leukemia
by: Anna Richter, et al.
Published: (2021-03-01)

Evolving therapy of adult acute lymphoblastic leukemia: state-of-the-art treatment and future directions
by: Bachar Samra, et al.
Published: (2020-06-01)

Targeted treatment of T-cell acute lymphoblastic leukemia: latest updates from the 2022 ASH Annual Meeting
by: Jieyu Xu, et al.
Published: (2023-03-01)

Case report: Treatment of two cases of recurrent/refractory early T-cell precursor acute lymphoblastic leukemia with venetoclax combined with the CAG regimen
by: Yuxia Jiang, et al.
Published: (2024-03-01)

Venetoclax durable response in adult relapsed/refractory Philadelphia-negative acute lymphoblastic leukemia with JAK/STAT pathway alterations
by: Anna Ferrari, et al.
Published: (2023-05-01)

IDH2-mutated near ETP-ALL with aggressive leukemia cutis and brisk response to venetoclax and decitabine
by: Poorva Vaidya, et al.
Published: (2024-01-01)

Biological Markers of High-Risk Childhood Acute Lymphoblastic Leukemia
by: Jiasen He, et al.
Published: (2024-02-01)

Clinical Profile and Induction Outcome of Children with T-cell Acute Lymphoblastic Leukemia and T-cell Lymphoblastic Lymphoma
by: Awais Arshed, et al.
Published: (2022-11-01)

Isatuximab monotherapy in patients with refractory T‐acute lymphoblastic leukemia or T‐lymphoblastic lymphoma: Phase 2 study
by: Nicolas Boissel, et al.
Published: (2022-03-01)

STAGE-DEPENDENT IMMUNOPATHOGENETIC FEATURES OF ACUTE NONLYMPHOBLASTIC AND ACUTE LYMPHOBLASTIC LEUKEMIA
by: O. V. Smirnova, et al.
Published: (2014-07-01)

Hyperoeosinophilia at diagnosis in adolescent acute lymphoblastic leukaemia/lymphoma: A case report and review of the literature
by: Dilshad Jahan, et al.
Published: (2020-01-01)

Venetoclax for Acute Myeloid Leukemia in Pediatric Patients: A Texas Medical Center Experience
by: Adriana Trabal, et al.
Published: (2023-03-01)

Aggressive lung involvement in a patient with T‐acute lymphoblastic leukaemia/lymphoblastic lymphoma: a tricky and rare case report
by: Chika Miyaoka, et al.
Published: (2020-08-01)

Osteonecrosis in Korean Paediatric and Young Adults with Acute Lymphoblastic Leukaemia or Lymphoblastic Lymphoma: A Nationwide Epidemiological Study
by: Seung Min Hahn, et al.
Published: (2022-04-01)

Complete remission in refractory acute lymphoblastic leukemia using blinatumomab after failure of response to CD‐19 chimeric antigen receptor T‐cell therapy
by: Francesco Paolo Tambaro, et al.
Published: (2020-09-01)

Acute lymphoblastic leukemia in a child presenting primarily with priapism
by: Garima Gupta, et al.
Published: (2020-01-01)

FEATURES OF IMMUNE CELLS IN ACUTE LYMPHOBLASTIC LEUKEMIA
by: O. V. Smirnova, et al.
Published: (2014-07-01)

Childhood Lymphoblastic Lymphoma: Hospital Based Study.
by: Samaher A. Fadhil, et al.
Published: (2015-01-01)

The Emerging Role of Venetoclax-Based Treatments in Acute Lymphoblastic Leukemia
by: Shlomzion Aumann, et al.
Published: (2022-09-01)

Inactivation of the p15 gene in children with acute lymphoblastic leukemia
by: Rosana Cipolotti, et al.

Pancytopenia - (?) An obstacle in the diagnosis and outcome of pediatric acute lymphoblastic leukemia
by: Shruti Raja, et al.
Published: (2015-01-01)

Acute Lymphoblastic Leukemia, Classification, Clinical features and Diagnosis
by: Fatimah Kadhim Ibrahim AL- Mahdawi, et al.
Published: (2020-12-01)

Acute Lymphoblastic Leukemia, Classification, Clinical features and Diagnosis
by: Fatimah Kadhim Ibrahim AL- Mahdawi, et al.
Published: (2020-12-01)

Targeted Therapy in Acute Lymphoblastic Leukaemia
by: Ross Salvaris, et al.
Published: (2021-07-01)

Impact of blinatumomab on patient outcomes in relapsed/refractory acute lymphoblastic leukemia: evidence to date
by: Hathaway L, et al.
Published: (2018-10-01)

Burden of hospitalization in acute lymphoblastic leukemia patients treated with Inotuzumab Ozogamicin versus standard chemotherapy treatment
by: David I. Marks, et al.
Published: (2019-10-01)

Possibilities of rehabilitation treatment of children with lymphoblastic leukemia (literary review)
by: S.V. Lukashchuk, et al.
Published: (2021-12-01)

Acute lymphoblastic leukemia and gingival enlargement – a case report
by: S. Gayathri, et al.
Published: (2021-09-01)

REMISSION RATE OF PRE-B ALL (ACUTE LYMPHOBLASTIC LEUKEMIA) AFTER INDUCTION CHEMOTHERAPY FOLLOWING UNITED KINGDOM ACUTE LYMPHOBLASTIC LEUKAEMIA 2011 (UKALL 2011) TRIAL PROTOCOL
by: Hafiz Muhammad Murtaza, et al.
Published: (2021-04-01)

Early diagnosis of childhood Acute lymphoblastic leukemia
by: Vanitha Pandey1, Mahesh Kumar K2,Indira3
Published: (2017-04-01)

ACUTE LYMPHOBLASTIC LEUKEMIA WITHOUT CIRCULATING BLASTS PRESENTING AS SEVERE HYPERCALCEMIA
by: Z. Oloomi
Published: (2007-02-01)

ACUTE LYMPHOBLASTIC LEUKEMIA WITHOUT CIRCULATING BLASTS PRESENTING AS SEVERE HYPERCALCEMIA
by: Z. Oloomi
Published: (2007-05-01)

Research progress in clinical characteristics, diagnosis and prognosis of TdT-negative lymphoblastic lymphoma/acute lymphoblastic leukemia
by: HOU Shumin, et al.
Published: (2023-01-01)

The Evolution of Chimeric Antigen Receptor T-Cell Therapy in Children, Adolescents and Young Adults with Acute Lymphoblastic Leukemia
by: Dristhi Ragoonanan, et al.
Published: (2022-09-01)

Proteomics in Childhood Acute Lymphoblastic Leukemia: Challenges and Opportunities
by: Maria Kourti, et al.
Published: (2023-08-01)

Hemostasis defects correction in children with acute lymphoblastic leukemia
by: A. S. Roshik, et al.
Published: (2022-11-01)

Rhodotorula fungemia in a patient with acute lymphoblastic leukemia
by: Mehmet Erinmez, et al.
Published: (2022-05-01)

Renal involvement at diagnosis of pediatric acute lymphoblastic leukemia
by: Mayerly Prada-Rico, et al.
Published: (2020-04-01)

Cytologic Phenotypes of B-Cell Acute Lymphoblastic Leukemia-
by: Ramyar Asghar, et al.
Published: (2009-06-01)

Two Cases of Cytomegalovirus Infection Developed in Pediatric Acute Lymphoblastic Leukemia Patients
by: Nayoung Jung, et al.
Published: (2019-10-01)