Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells

Differential Contribution of NF-κB Signaling Pathways to CD4+ Memory T Cell Induced Activation of Endothelial Cells

Endothelial cells (ECs) are important contributors to inflammation in immune-mediated inflammatory diseases (IMIDs). In this study, we examined whether CD4+ memory T (Tm) cells can drive EC inflammatory responses. Human Tm cells produced ligands that induced inflammatory responses in human umbilical...

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Bibliographic Details
Main Authors: Kim C. M. Jeucken, Charlotte C. N. van Rooijen, Yik Y. Kan, Lotte A. Kocken, Aldo Jongejan, Abraham C. I. van Steen, Jaap D. van Buul, Henric K. Olsson, Jan Piet van Hamburg, Sander W. Tas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
endothelial (dys)function
inflammation
immune mediated disorders
CD4+ memory T cells
NF-kB signaling
cellular interaction
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.860327/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.860327/full

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