Safe Nanoparticles: Are We There Yet?
The field of nanotechnology has grown over the last two decades and made the transition from the benchtop to applied technologies. Nanoscale-sized particles, or nanoparticles, have emerged as promising tools with broad applications in drug delivery, diagnostics, cosmetics and several other biologica...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-12-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/22/1/385 |
| _version_ | 1797542740800569344 |
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| author | Wided Najahi-Missaoui Robert D. Arnold Brian S. Cummings |
| author_facet | Wided Najahi-Missaoui Robert D. Arnold Brian S. Cummings |
| author_sort | Wided Najahi-Missaoui |
| collection | DOAJ |
| description | The field of nanotechnology has grown over the last two decades and made the transition from the benchtop to applied technologies. Nanoscale-sized particles, or nanoparticles, have emerged as promising tools with broad applications in drug delivery, diagnostics, cosmetics and several other biological and non-biological areas. These advances lead to questions about nanoparticle safety. Despite considerable efforts to understand the toxicity and safety of these nanoparticles, many of these questions are not yet fully answered. Nevertheless, these efforts have identified several approaches to minimize and prevent nanoparticle toxicity to promote safer nanotechnology. This review summarizes our current knowledge on nanoparticles, their toxic effects, their interactions with mammalian cells and finally current approaches to minimizing their toxicity. |
| first_indexed | 2024-03-10T13:34:51Z |
| format | Article |
| id | doaj.art-61200dd5712e4563ac8552417d278ee2 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-10T13:34:51Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-61200dd5712e4563ac8552417d278ee22023-11-21T07:38:28ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672020-12-0122138510.3390/ijms22010385Safe Nanoparticles: Are We There Yet?Wided Najahi-Missaoui0Robert D. Arnold1Brian S. Cummings2Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USADepartment of Drug Discovery & Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USADepartment of Pharmaceutical and Biomedical Sciences, College of Pharmacy, University of Georgia, Athens, GA 30602, USAThe field of nanotechnology has grown over the last two decades and made the transition from the benchtop to applied technologies. Nanoscale-sized particles, or nanoparticles, have emerged as promising tools with broad applications in drug delivery, diagnostics, cosmetics and several other biological and non-biological areas. These advances lead to questions about nanoparticle safety. Despite considerable efforts to understand the toxicity and safety of these nanoparticles, many of these questions are not yet fully answered. Nevertheless, these efforts have identified several approaches to minimize and prevent nanoparticle toxicity to promote safer nanotechnology. This review summarizes our current knowledge on nanoparticles, their toxic effects, their interactions with mammalian cells and finally current approaches to minimizing their toxicity.https://www.mdpi.com/1422-0067/22/1/385nanoparticlesnanotechnologytoxicologycellular interactionsdrug deliverysafe nanoparticles |
| spellingShingle | Wided Najahi-Missaoui Robert D. Arnold Brian S. Cummings Safe Nanoparticles: Are We There Yet? International Journal of Molecular Sciences nanoparticles nanotechnology toxicology cellular interactions drug delivery safe nanoparticles |
| title | Safe Nanoparticles: Are We There Yet? |
| title_full | Safe Nanoparticles: Are We There Yet? |
| title_fullStr | Safe Nanoparticles: Are We There Yet? |
| title_full_unstemmed | Safe Nanoparticles: Are We There Yet? |
| title_short | Safe Nanoparticles: Are We There Yet? |
| title_sort | safe nanoparticles are we there yet |
| topic | nanoparticles nanotechnology toxicology cellular interactions drug delivery safe nanoparticles |
| url | https://www.mdpi.com/1422-0067/22/1/385 |
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