Discordance of tuberculin skin test and interferon gamma release assay in recently exposed household contacts of pulmonary TB cases in Brazil.

Discordance of tuberculin skin test and interferon gamma release assay in recently exposed household contacts of pulmonary TB cases in Brazil.

Interferon-gamma (IFN-γ) release assays (IGRAs) such as the Quantiferon Gold In-tube test are in vitro assays that measure IFN-γ release from T cells in response to M. tuberculosis (Mtb)-specific antigens. Unlike the tuberculin skin test (TST), IGRA is specific and able to distinguish Mtb-infection...

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Bibliographic Details
Main Authors: Rodrigo Ribeiro-Rodrigues, Soyeon Kim, Flávia Dias Coelho da Silva, Aleksandra Uzelac, Lauren Collins, Moíses Palaci, David Alland, Reynaldo Dietze, Jerrold J Ellner, Edward Jones-López, Padmini Salgame
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4018294?pdf=render

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