Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination
Rupture of pseudoaneurysms is rare but can be life-threatening complications of acute or chronic pancreatitis, usually due to enzymatic digestion of vessel walls crossing peripancreatic fluid collections. We report the case of a 40 year-old female, with multisystemic lupus and anticoagulated for pri...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2016-11-01
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| Series: | GE: Portuguese Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2341454516300497 |
| _version_ | 1828189894970703872 |
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| author | Diogo Branquinho Daniel Ramos-Andrade Luís Elvas Pedro Amaro Manuela Ferreira Carlos Sofia |
| author_facet | Diogo Branquinho Daniel Ramos-Andrade Luís Elvas Pedro Amaro Manuela Ferreira Carlos Sofia |
| author_sort | Diogo Branquinho |
| collection | DOAJ |
| description | Rupture of pseudoaneurysms is rare but can be life-threatening complications of acute or chronic pancreatitis, usually due to enzymatic digestion of vessel walls crossing peripancreatic fluid collections. We report the case of a 40 year-old female, with multisystemic lupus and anticoagulated for prior thrombotic events, admitted for probable cyclosporine-induced acute pancreatitis. Hemodynamic instability occurred due to abdominal hemorrhage from two pseudoaneurysms inside an acute peri-pancreatic collection. Selective angiography successfully embolized the gastroduodenal and pancreatoduodenal arteries. The hemorrhage recurred two weeks later and another successful embolization was performed and the patient remains well to date. The decision to restart anticoagulants and to suspend cyclosporine was challenging and required a multidisciplinary approach. Despite rare, bleeding from a pseudoaneurysm should be considered when facing a patient with pancreatitis and sudden signs of hemodynamic instability. |
| first_indexed | 2024-04-12T08:12:19Z |
| format | Article |
| id | doaj.art-612c1ab1658d4b65b476ecfad47c892b |
| institution | Directory Open Access Journal |
| issn | 2341-4545 |
| language | English |
| last_indexed | 2024-04-12T08:12:19Z |
| publishDate | 2016-11-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | GE: Portuguese Journal of Gastroenterology |
| spelling | doaj.art-612c1ab1658d4b65b476ecfad47c892b2022-12-22T03:40:55ZengKarger PublishersGE: Portuguese Journal of Gastroenterology2341-45452016-11-0123630931310.1016/j.jpge.2016.06.002Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous CombinationDiogo BranquinhoDaniel Ramos-AndradeLuís ElvasPedro AmaroManuela FerreiraCarlos SofiaRupture of pseudoaneurysms is rare but can be life-threatening complications of acute or chronic pancreatitis, usually due to enzymatic digestion of vessel walls crossing peripancreatic fluid collections. We report the case of a 40 year-old female, with multisystemic lupus and anticoagulated for prior thrombotic events, admitted for probable cyclosporine-induced acute pancreatitis. Hemodynamic instability occurred due to abdominal hemorrhage from two pseudoaneurysms inside an acute peri-pancreatic collection. Selective angiography successfully embolized the gastroduodenal and pancreatoduodenal arteries. The hemorrhage recurred two weeks later and another successful embolization was performed and the patient remains well to date. The decision to restart anticoagulants and to suspend cyclosporine was challenging and required a multidisciplinary approach. Despite rare, bleeding from a pseudoaneurysm should be considered when facing a patient with pancreatitis and sudden signs of hemodynamic instability.http://www.sciencedirect.com/science/article/pii/S2341454516300497Aneurysm, FalseEmbolization, TherapeuticPancreatitis/chemically induced |
| spellingShingle | Diogo Branquinho Daniel Ramos-Andrade Luís Elvas Pedro Amaro Manuela Ferreira Carlos Sofia Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination GE: Portuguese Journal of Gastroenterology Aneurysm, False Embolization, Therapeutic Pancreatitis/chemically induced |
| title | Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination |
| title_full | Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination |
| title_fullStr | Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination |
| title_full_unstemmed | Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination |
| title_short | Drug-Induced Acute Pancreatitis and Pseudoaneurysms: An Ominous Combination |
| title_sort | drug induced acute pancreatitis and pseudoaneurysms an ominous combination |
| topic | Aneurysm, False Embolization, Therapeutic Pancreatitis/chemically induced |
| url | http://www.sciencedirect.com/science/article/pii/S2341454516300497 |
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