Characterization of collagen response to bone fracture healing using polarization-SHG

Abstract In this study, we extend on the three parameter analysis approach of utilizing a noninvasive dual-liquid–crystal-based polarization-resolved second harmonic generation (SHG) microscopy to facilitate the quantitative characterization of collagen types I and II in fracture healing tissues. Th...

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Bibliographic Details
Main Authors: Anupama Nair, Shu-Chun Chuang, Yi-Shan Lin, Chung-Hwan Chen, Ting-Chen Fang, Hsiao-Chi Chiu, Chi-Hsiang Lien, Shean-Jen Chen
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-21876-z

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