Advances in multimodality molecular imaging

Multimodality molecular imaging using high resolution positron emission tomography (PET) combined with other modalities is now playing a pivotal role in basic and clinical research. The introduction of combined PET/CT systems in clinical setting has revolutionized the practice of diagnostic imaging....

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Main Authors: Zaidi Habib, Prasad Rameshwar
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2009-01-01
Series:Journal of Medical Physics
Subjects:
Online Access:http://www.jmp.org.in/article.asp?issn=0971-6203;year=2009;volume=34;issue=3;spage=122;epage=128;aulast=Zaidi
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author Zaidi Habib
Prasad Rameshwar
author_facet Zaidi Habib
Prasad Rameshwar
author_sort Zaidi Habib
collection DOAJ
description Multimodality molecular imaging using high resolution positron emission tomography (PET) combined with other modalities is now playing a pivotal role in basic and clinical research. The introduction of combined PET/CT systems in clinical setting has revolutionized the practice of diagnostic imaging. The complementarity between the intrinsically aligned anatomic (CT) and functional or metabolic (PET) information provided in a "one-stop shop" and the possibility to use CT images for attenuation correction of the PET data has been the driving force behind the success of this technology. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) in a single gantry is technically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of few preclinical PET systems and one human prototype dedicated for simultaneous PET/MR brain imaging. This paper discusses recent advances in PET instrumentation and the advantages and challenges of multimodality imaging systems. Future opportunities and the challenges facing the adoption of multimodality imaging instrumentation will also be addressed.
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spelling doaj.art-613071219e1744d8a7c18427c9db93802022-12-22T03:20:02ZengWolters Kluwer Medknow PublicationsJournal of Medical Physics0971-62031998-39132009-01-01343122128Advances in multimodality molecular imagingZaidi HabibPrasad RameshwarMultimodality molecular imaging using high resolution positron emission tomography (PET) combined with other modalities is now playing a pivotal role in basic and clinical research. The introduction of combined PET/CT systems in clinical setting has revolutionized the practice of diagnostic imaging. The complementarity between the intrinsically aligned anatomic (CT) and functional or metabolic (PET) information provided in a "one-stop shop" and the possibility to use CT images for attenuation correction of the PET data has been the driving force behind the success of this technology. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) in a single gantry is technically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of few preclinical PET systems and one human prototype dedicated for simultaneous PET/MR brain imaging. This paper discusses recent advances in PET instrumentation and the advantages and challenges of multimodality imaging systems. Future opportunities and the challenges facing the adoption of multimodality imaging instrumentation will also be addressed.http://www.jmp.org.in/article.asp?issn=0971-6203;year=2009;volume=34;issue=3;spage=122;epage=128;aulast=ZaidiInstrumentationmultimodality imagingPETPET/CTPET/MR
spellingShingle Zaidi Habib
Prasad Rameshwar
Advances in multimodality molecular imaging
Journal of Medical Physics
Instrumentation
multimodality imaging
PET
PET/CT
PET/MR
title Advances in multimodality molecular imaging
title_full Advances in multimodality molecular imaging
title_fullStr Advances in multimodality molecular imaging
title_full_unstemmed Advances in multimodality molecular imaging
title_short Advances in multimodality molecular imaging
title_sort advances in multimodality molecular imaging
topic Instrumentation
multimodality imaging
PET
PET/CT
PET/MR
url http://www.jmp.org.in/article.asp?issn=0971-6203;year=2009;volume=34;issue=3;spage=122;epage=128;aulast=Zaidi
work_keys_str_mv AT zaidihabib advancesinmultimodalitymolecularimaging
AT prasadrameshwar advancesinmultimodalitymolecularimaging