Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231
The use of herbal plant for treatment and prevention of diseases is getting more popular, emphasizing the need for studies on active compounds from plants. Ant hill (Myrmecodia pendens) contains active compounds such as terpenoid, tannin, phenol, flavonoid, and saponin which have antifungal effects...
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| Format: | Article |
| Language: | English |
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Universitas Padjajaran
2017-03-01
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| Series: | Majalah Kedokteran Bandung |
| Subjects: | |
| Online Access: | http://journal.fk.unpad.ac.id/index.php/mkb/article/view/984 |
| _version_ | 1818523136336855040 |
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| author | Felisha Febriane Balafif Mieke Hemiawati Satari Diah Dhianawaty |
| author_facet | Felisha Febriane Balafif Mieke Hemiawati Satari Diah Dhianawaty |
| author_sort | Felisha Febriane Balafif |
| collection | DOAJ |
| description | The use of herbal plant for treatment and prevention of diseases is getting more popular, emphasizing the need for studies on active compounds from plants. Ant hill (Myrmecodia pendens) contains active compounds such as terpenoid, tannin, phenol, flavonoid, and saponin which have antifungal effects on Candida albicans. The objectives of the study were to measure the value of minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of water fraction of M. pendens and antifungal effect of water fractions of M. pendens against C. albicans compared to nystatin. This study used microdilution and the effects were measured with enzyme linked immunosorbent assay reader to determine MIC value, followed by agar media assay to determine MFC. Data were analyzed using T test with significant level p < 0.05 to determine antifungal effect of water fractions of M. pendens against C. albicans compared to nystatin. The result showed that MIC value was 1.250 μg/ml and MFC value was 2.500 μg/ml. T test showed significant difference of % inhibition cells growth effect between M. pendens water fraction and nystatin (p=0.014 < 0.05). It is concluded that the M. pendens water fraction has an antifungal effect against C. albicans with MIC and MFC values of 1.250 and 2.500 μg/ml.There are differences in antifungal effects between water fraction of M. pendens and nystatin against C. albicans. |
| first_indexed | 2024-12-11T05:41:28Z |
| format | Article |
| id | doaj.art-6133d54d5ee14433b9a5018f047d553c |
| institution | Directory Open Access Journal |
| issn | 0126-074X 2338-6223 |
| language | English |
| last_indexed | 2024-12-11T05:41:28Z |
| publishDate | 2017-03-01 |
| publisher | Universitas Padjajaran |
| record_format | Article |
| series | Majalah Kedokteran Bandung |
| spelling | doaj.art-6133d54d5ee14433b9a5018f047d553c2022-12-22T01:19:07ZengUniversitas PadjajaranMajalah Kedokteran Bandung0126-074X2338-62232017-03-01491283410.15395/mkb.v49n1.984Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231Felisha Febriane BalafifMieke Hemiawati SatariDiah DhianawatyThe use of herbal plant for treatment and prevention of diseases is getting more popular, emphasizing the need for studies on active compounds from plants. Ant hill (Myrmecodia pendens) contains active compounds such as terpenoid, tannin, phenol, flavonoid, and saponin which have antifungal effects on Candida albicans. The objectives of the study were to measure the value of minimum inhibitory concentration (MIC) and the minimum fungicidal concentration (MFC) of water fraction of M. pendens and antifungal effect of water fractions of M. pendens against C. albicans compared to nystatin. This study used microdilution and the effects were measured with enzyme linked immunosorbent assay reader to determine MIC value, followed by agar media assay to determine MFC. Data were analyzed using T test with significant level p < 0.05 to determine antifungal effect of water fractions of M. pendens against C. albicans compared to nystatin. The result showed that MIC value was 1.250 μg/ml and MFC value was 2.500 μg/ml. T test showed significant difference of % inhibition cells growth effect between M. pendens water fraction and nystatin (p=0.014 < 0.05). It is concluded that the M. pendens water fraction has an antifungal effect against C. albicans with MIC and MFC values of 1.250 and 2.500 μg/ml.There are differences in antifungal effects between water fraction of M. pendens and nystatin against C. albicans.http://journal.fk.unpad.ac.id/index.php/mkb/article/view/984Candida albicansminimum fungicidal concentrationminimum inhibitory concentrationMyrmecodia pendenswater fraction |
| spellingShingle | Felisha Febriane Balafif Mieke Hemiawati Satari Diah Dhianawaty Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 Majalah Kedokteran Bandung Candida albicans minimum fungicidal concentration minimum inhibitory concentration Myrmecodia pendens water fraction |
| title | Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 |
| title_full | Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 |
| title_fullStr | Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 |
| title_full_unstemmed | Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 |
| title_short | Aktivitas Antijamur Fraksi Air Sarang Semut Myrmecodia Pendens Pada Candida Albicans ATCC 10231 |
| title_sort | aktivitas antijamur fraksi air sarang semut myrmecodia pendens pada candida albicans atcc 10231 |
| topic | Candida albicans minimum fungicidal concentration minimum inhibitory concentration Myrmecodia pendens water fraction |
| url | http://journal.fk.unpad.ac.id/index.php/mkb/article/view/984 |
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