MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination

Detecting cancer disease at an early stage is one of the most important issues for increasing the survival rate of patients. Cancer biomarker detection helps to provide a diagnosis before the disease becomes incurable in later stages. Biomarkers can also be used to evaluate the progression of therap...

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Main Authors: Giulia Selvolini, Giovanna Marrazza
Format: Article
Language:English
Published: MDPI AG 2017-03-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/17/4/718
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author Giulia Selvolini
Giovanna Marrazza
author_facet Giulia Selvolini
Giovanna Marrazza
author_sort Giulia Selvolini
collection DOAJ
description Detecting cancer disease at an early stage is one of the most important issues for increasing the survival rate of patients. Cancer biomarker detection helps to provide a diagnosis before the disease becomes incurable in later stages. Biomarkers can also be used to evaluate the progression of therapies and surgery treatments. In recent years, molecularly imprinted polymer (MIP) based sensors have been intensely investigated as promising analytical devices in several fields, including clinical analysis, offering desired portability, fast response, specificity, and low cost. The aim of this review is to provide readers with an overview on recent important achievements in MIP-based sensors coupled to various transducers (e.g., electrochemical, optical, and piezoelectric) for the determination of cancer biomarkers by selected publications from 2012 to 2016.
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spelling doaj.art-6136d59d292f4c0398389427bd6e6c652022-12-22T02:18:13ZengMDPI AGSensors1424-82202017-03-0117471810.3390/s17040718s17040718MIP-Based Sensors: Promising New Tools for Cancer Biomarker DeterminationGiulia Selvolini0Giovanna Marrazza1Department of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3, Sesto Fiorentino 50019, ItalyDepartment of Chemistry “Ugo Schiff”, University of Florence, Via della Lastruccia 3, Sesto Fiorentino 50019, ItalyDetecting cancer disease at an early stage is one of the most important issues for increasing the survival rate of patients. Cancer biomarker detection helps to provide a diagnosis before the disease becomes incurable in later stages. Biomarkers can also be used to evaluate the progression of therapies and surgery treatments. In recent years, molecularly imprinted polymer (MIP) based sensors have been intensely investigated as promising analytical devices in several fields, including clinical analysis, offering desired portability, fast response, specificity, and low cost. The aim of this review is to provide readers with an overview on recent important achievements in MIP-based sensors coupled to various transducers (e.g., electrochemical, optical, and piezoelectric) for the determination of cancer biomarkers by selected publications from 2012 to 2016.http://www.mdpi.com/1424-8220/17/4/718sensorMIPsmolecularly imprinted polymerbiomarkercancertumor
spellingShingle Giulia Selvolini
Giovanna Marrazza
MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
Sensors
sensor
MIPs
molecularly imprinted polymer
biomarker
cancer
tumor
title MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
title_full MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
title_fullStr MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
title_full_unstemmed MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
title_short MIP-Based Sensors: Promising New Tools for Cancer Biomarker Determination
title_sort mip based sensors promising new tools for cancer biomarker determination
topic sensor
MIPs
molecularly imprinted polymer
biomarker
cancer
tumor
url http://www.mdpi.com/1424-8220/17/4/718
work_keys_str_mv AT giuliaselvolini mipbasedsensorspromisingnewtoolsforcancerbiomarkerdetermination
AT giovannamarrazza mipbasedsensorspromisingnewtoolsforcancerbiomarkerdetermination